Dilated cardiomyopathy and chronic cardiac inflammation: Pathogenesis, diagnosis and therapy

D Harding, MHA Chong, N Lahoti… - Journal of internal …, 2023 - Wiley Online Library
Dilated cardiomyopathy (DCM) is typically defined by left ventricular dilation and systolic
dysfunction in the absence of a clear precipitant. Idiopathic disease is common; up to 50% of …

The roles of TNF in brain dysfunction and disease

IA Clark, LM Alleva, B Vissel - Pharmacology & therapeutics, 2010 - Elsevier
Certain cytokines, the prototype being the highly pleiotropic TNF, have many homeostatic
physiological roles, are involved in innate immunity, and cause inflammation when in …

[HTML][HTML] Treatment options in myocarditis and inflammatory cardiomyopathy: Focus on iv immunoglobulins

B Maisch, P Alter - Herz, 2018 - ncbi.nlm.nih.gov
For myocarditis and inflammatory cardiomyopathy, an etiologically driven treatment is today
the best option beyond heart failure therapy. Prerequisites for this are noninvasive and …

Use of intravenous gamma globulin and corticosteroids in the treatment of maternal autoantibody-mediated cardiomyopathy

SM Trucco, E Jaeggi, B Cuneo, AJ Moon-Grady… - Journal of the American …, 2011 - jacc.org
Objectives: This study sought to evaluate the outcome of maternal autoantibody-mediated
fetal cardiomyopathy/endocardial fibroelastosis following intravenous gamma globulin (IVIG) …

Cytokines and acute heart failure

D Chen, C Assad-Kottner, C Orrego… - Critical care …, 2008 - journals.lww.com
In patients with chronic heart failure, ongoing myocardial injury partially results from
activation of the inflammatory system, with production and release of proinflammatory …

Evidence for the use of intravenous immunoglobulins—a review of the literature

S Kivity, U Katz, N Daniel, U Nussinovitch… - Clinical reviews in …, 2010 - Springer
Intravenous immunoglobulins (IVIg) were first introduced in the middle of the twentieth
century for the treatment of primary immunodeficiencies. In 1981, Paul Imbach noticed an …

[PDF][PDF] Treatment of inflammatory dilated cardiomyopathy and (peri) myocarditis with immunosuppression and iv immunoglobulins

B Maisch, G Hufnagel, S Kölsch, R Funck, A Richter… - Herz, 2004 - academia.edu
Objectives: Treatment objectives in inflammatory dilated cardiomyopathy (DCMi),
myocarditis (M) and peri (myo) carditis are 1) the elimination of inflammatory cells from the …

[HTML][HTML] The role of microbiota and oxidative stress axis and the impact of intravenous immunoglobulin in systemic lupus erythematosus

MG Danieli, E Antonelli, E Longhi, S Gangemi… - Autoimmunity …, 2024 - Elsevier
Systemic lupus erythematosus (SLE) is a complex autoimmune disease characterized by
widespread inflammation affecting various organs. This review discusses the role of …

Emerging pharmacologic targets and treatments for myocarditis

LD Jensen, DJ Marchant - Pharmacology & Therapeutics, 2016 - Elsevier
Myocarditis is a heterogeneous group of disorders defined by inflammation of the heart
muscle. The primary clinical manifestations of myocarditis are heart failure and sudden …

Standard and etiology-directed evidence-based therapies in myocarditis: state of the art and future perspectives

B Maisch, S Pankuweit - Heart failure reviews, 2013 - Springer
In inflammatory dilated cardiomyopathy and myocarditis, there is apart from heart failure and
antiarrhythmic therapies no alternative to an etiologically driven specific treatment. Their …