The first human tumor virus was discovered in the middle of the last century by Anthony
Epstein, Bert Achong and Yvonne Barr in African pediatric patients with Burkitt's lymphoma …

Kaposi's sarcoma–associated herpesvirus produces a highly abundant, nuclear noncoding
RNA, polyadenylated nuclear (PAN) RNA, which contains an element that prevents its …

Purpose. The characteristics, etiology, natural history, and direct and indirect effects of CMV
disease in solid organ transplant recipients are described. Summary. CMV is a common …

Cellular RNAs are subject to quality-control pathways that insure the fidelity of gene
expression. We previously identified a 79 nt element, the ENE, that is essential for the …

Kaposi sarcoma-associated herpesvirus (KSHV) ORF57, also known as Mta (m RNA t
ranscript a ccumulation), enhances viral intron-less transcript accumulation and promotes …

Background: Malignant lymphoma (ML) in HIV patients, are second in frequency to Kaposi's
sarcoma (AKS) as AIDS-defining tumors. In Africa the frequency of AIDS-related lymphoma …

Gammaherpesviruses are agents which have evolved to persist within the lymphoid system
and many have oncogenic potential; studying gammaherpesvirus infections therefore has …

Disease characteristics. Common variable immune deficiency (CVID) is characterized by
humoral immune deficiency with onset after 24 months of age and usually in young …

Tumor viruses are linked to approximately 20% of human malignancies worldwide. This
review focuses on examples of human oncogenic viruses that manipulate the ubiquitin …

Gammaherpesviruses establish life-long latent infections in their hosts. If the host becomes
immunosuppressed, these viruses may reactivate and cause severe disease, and even in …