The liposomes have continued to be well-recognized as an important nano-sized drug
delivery system with attractive properties, such a characteristic bilayer structure assembling …

Neurodegenerative disorders (NDDs) are a group of chronic progressive neurological
diseases based on primary neurodegeneration. The common pathological characteristics of …

Rationale: Glial scars present a major obstacle for neuronal regeneration after stroke. Thus,
approaches to promote their degradation and inhibit their formation are beneficial for stroke …

Abstract DAPT (N-[N-(3, 5-difluorophenacetyl)-l-alanyl]-s-phenylglycinet-butyl ester) is a γ-
secretase inhibitor that indirectly blocks the activity of Notch pathway. It is a potential …

Abstract miRNAs are promising therapeutic targets or tools for the treatment of numerous
diseases, with most prominently, cancer. The inherent capacity of these short nucleic acids …

Abstract miR-124 is a miRNA predominantly expressed in the nervous system and accounts
for more than a quarter of the total miRNAs in the brain. It regulates neurogenesis, neuronal …

Abstract Development of the complex human heart is tightly regulated at multiple levels,
maintaining multipotency and proliferative state in the embryonic cardiovascular progenitors …

Regeneration of lost body parts is essential to regain the fitness of the organism for
successful living. In the animal kingdom, organisms from different clades exhibit varied …

Central nervous system injuries and diseases, such as ischemic stroke, spinal cord injury,
neurodegenerative diseases, glioblastoma, multiple sclerosis, and the resulting …

During neuronal development and regeneration axons extend a cytoskeletal-rich structure
known as the growth cone, which detects and integrates signals to reach its final destination …