Platelet integrin αIIbβ3: signal transduction, regulation, and its therapeutic targeting

J Huang, X Li, X Shi, M Zhu, J Wang, S Huang… - Journal of hematology & …, 2019 - Springer
Integrins are a family of transmembrane glycoprotein signaling receptors that can transmit
bioinformation bidirectionally across the plasma membrane. Integrin αIIbβ3 is expressed at a …

Anti-inflammatory therapies for atherosclerosis

M Bäck, GK Hansson - Nature Reviews Cardiology, 2015 - nature.com
The view of atherosclerosis as an inflammatory disease has emerged from observations of
immune activation and inflammatory signalling in human atherosclerotic lesions, from the …

ACC/AHA 2007 guidelines for the management of patients with unstable angina/non–ST-elevation myocardial infarction: a report of the American College of …

JL Anderson, CD Adams, EM Antman… - Journal of the American …, 2007 - jacc.org
The ACC/AHA Task Force on Practice Guidelines was formed to make recommendations
regarding the diagnosis and treatment of patients with known or suspected cardiovascular …

Stopping randomized trials early for benefit and estimation of treatment effects: systematic review and meta-regression analysis

D Bassler, M Briel, VM Montori, M Lane, P Glasziou… - Jama, 2010 - jamanetwork.com
Context Theory and simulation suggest that randomized controlled trials (RCTs) stopped
early for benefit (truncated RCTs) systematically overestimate treatment effects for the …

ACC/AHA/SCAI 2005 guideline update for percutaneous coronary intervention: a report of the American College of Cardiology/American Heart Association Task Force …

SC Smith Jr, TE Feldman, JW Hirshfeld Jr… - Journal of the American …, 2006 - Elsevier
The ACC/AHA Task Force on Practice Guidelines was formed to gather information and
make recommendations about appropriate use of technology for the diagnosis and …

Marked inflammatory sequelae to implantation of biodegradable and nonbiodegradable polymers in porcine coronary arteries

WJ Van der Giessen, AM Lincoff, RS Schwartz… - Circulation, 1996 - Am Heart Assoc
Background With the thrombogenic tendency and permanent implant nature of metallic
stents, synthetic polymers have been proposed as candidate materials for stents and local …

2011 ACCF/AHA focused update incorporated into the ACC/AHA 2007 guidelines for the management of patients with unstable angina/non–ST-elevation myocardial …

JL Anderson, CD Adams, EM Antman, CR Bridges… - Circulation, 2011 - Am Heart Assoc
2011 ACCF/AHA Focused Update Incorporated Into the ACC/AHA 2007 Guidelines for the
Management of Patients With Unstable Angina/Non–ST-Elevation Myocardial Infarction …

Drug delivery by red blood cells: vascular carriers designed by mother nature

VR Muzykantov - Expert opinion on drug delivery, 2010 - Taylor & Francis
Importance of the field: Vascular delivery of several classes of therapeutic agents may
benefit from carriage by red blood cells (RBC), for example, drugs that require delivery into …

ACC/AHA guidelines for the management of patients with unstable angina and non–ST-segment elevation myocardial infarction: a report of the American College of …

E Braunwald, EM Antman, JW Beasley… - Journal of the American …, 2000 - jacc.org
Conclusions...... 1025 V. Hospital Discharge and Post–Hospital Discharge Care...... 1025 A.
Medical Regimen...... 1026 1. Long-Term Medical Therapy...... 1026 B. Postdischarge Follow …

von Willebrand factor: a marker of endothelial dysfunction in vascular disorders?

GYH Lip, A Blann - Cardiovascular research, 1997 - academic.oup.com
The vascular endothelium is involved in the production of many important substances which
are involved in cardiovascular pathophysiology. One such substance which is synthesised …