[HTML][HTML] Single-cell protein activity analysis identifies recurrence-associated renal tumor macrophages

A Obradovic, N Chowdhury, SM Haake, C Ager… - Cell, 2021 - cell.com
Clear cell renal carcinoma (ccRCC) is a heterogeneous disease with a variable post-
surgical course. To assemble a comprehensive ccRCC tumor microenvironment (TME) …

Active surveillance of renal masses: the role of radiology

N Schieda, S Krishna, I Pedrosa, SD Kaffenberger… - Radiology, 2022 - pubs.rsna.org
Active surveillance of renal masses, which includes serial imaging with the possibility of
delayed treatment, has emerged as a viable alternative to immediate therapeutic …

FADS2 function at the major cancer hotspot 11q13 locus alters fatty acid metabolism in cancer

KSD Kothapalli, HG Park, NSL Kothapalli… - Progress in Lipid …, 2023 - Elsevier
Dysregulation of fatty acid metabolism and de novo lipogenesis is a key driver of several
cancer types through highly unsaturated fatty acid (HUFA) signaling precursors such as …

Diagnostic liquid biopsy biomarkers in renal cell cancer

RC Zieren, PJ Zondervan, KJ Pienta, A Bex… - Nature Reviews …, 2024 - nature.com
The clinical presentation of renal cell cancer (RCC) is shifting towards incidental and early
detection, creating new challenges in RCC diagnosis. Overtreatment might be reduced with …

Serum tumor markers for early diagnosis of primary hepatocellular carcinoma

J Zong, Z Fan, Y Zhang - Journal of hepatocellular carcinoma, 2020 - Taylor & Francis
Primary hepatocellular carcinoma (HCC) is one of the most frequently occurring pernicious
tumors in the world. It is typically very insidious in the early stages with no obvious …

Advances in imaging-based biomarkers in renal cell carcinoma: a critical analysis of the current literature

L Posada Calderon, L Eismann, SW Reese, E Reznik… - Cancers, 2023 - mdpi.com
Simple Summary Current imaging techniques do not reliably distinguish renal cell
carcinoma from other renal diseases. This review summarizes recent advances in other …

LiKidMiRs: A ddPCR-based panel of 4 circulating miRNAs for detection of renal cell carcinoma

JP Sequeira, V Constâncio, S Salta, J Lobo… - Cancers, 2022 - mdpi.com
Simple Summary Early detection of renal cell carcinoma (RCC) significantly increases the
likelihood of curative treatment, avoiding the need of adjuvant therapies, associated side …

The role of chemokine receptor CXCR3 and its ligands in renal cell carcinoma

M Gudowska-Sawczuk, J Kudelski… - International Journal of …, 2020 - mdpi.com
The major invasive subtype of kidney cancer is renal cell carcinoma (RCC). The essential
components of cancer development are chronic inflammation and neoangiogenesis. It has …

Early detection of kidney cancer using urinary proteins: a truly non‐invasive strategy

JG Flitcroft, J Verheyen, T Vemulkar… - BJU …, 2022 - Wiley Online Library
Objectives To review urinary protein biomarkers as potential non‐invasive, easily
obtainable, early diagnostic tools in renal cell carcinoma (RCC). Methods A PubMed …

Novel emerging biomarkers to immunotherapy in kidney cancer

Y Ged, MH Voss - Therapeutic Advances in Medical …, 2021 - journals.sagepub.com
The treatment of metastatic renal cell carcinoma has significantly evolved in recent years,
particularly with the advent of novel immune checkpoint inhibitors (ICI). Despite the striking …