Background Ketamine infusions have been used for decades to treat acute pain, but a
recent surge in usage has made the infusions a mainstay of treatment in emergency …

Pain is the leading cause of medical consultations and occurs in 50–70% of emergency
department visits. To date, several drugs have been used to manage pain. The clinical use …

Acute pain is one of the most common symptoms in children admitted to the Pediatric
Emergency Department (PED) and its management represents a real clinical challenge for …

Peri-operative pain management is one of the important tasks of medical staff. The problems
arising afterwards not only have a pathophysiological adverse effect on patients, but also …

Electroconvulsive therapy (ECT) is a safe and effective treatment for catatonia with high
response rates. Although empirical data suggest that tolerability and efficacy are at least as …

Background Intranasal procedural sedation using dexmedetomidine is well described in the
literature. The combination of intranasal dexmedetomidine and ketamine is a novel …

Background We investigated the effects of ketamine on desaturation and the risk of nursing
home discharge in patients undergoing procedural sedation by anaesthetists. Methods We …

Ketamine is a versatile drug with a unique profile that allows it to be successfully used for a
multitude of situations worldwide. Its variable dosing means it can be used both as an …

Due to overcrowding, personnel shortages, or problematic intravenous (IV) cannulation,
acute pain management is often sub-optimal in emergency departments (EDs). The …

Initially known as CI-581, ketamine was first synthesized in 1962 as a replacement from
phencyclidine. It has since been used as an anesthetic and analgesic. In addition, it has …