Arynes are among the most active organic intermediates and have found numerous
applications in expeditious preparation of substituted arenes. In the past 20 years, chemists …

Conspectus Arynes are highly reactive intermediates having several applications in organic
synthesis for the construction of various ortho-disubstituted arenes. Traditionally, arynes are …

The transition-metal-free multicomponent coupling involving arynes, aromatic tertiary
amines, and CO2 is reported. The reaction exhibits switchable selectivity depending on the …

Organosulfides are a common class of structure units in bioactive molecules and functional
materials motivating continuous developments of efficient synthetic methods. Herein, we …

The transition-metal-free and temperature-dependent highly selective reaction of arynes
with 2 H-azirines allowing the synthesis of either N-unsubstituted or N-arylindoles has been …

The synthetic potential of thiophenols as a protic nucleophilic trigger in the transition-metal-
free and Grignard-reagent-free three-component coupling involving arynes is demonstrated …

Efficient annulation of benzamides with arynes using palladium and photoredox dual
catalysis under an oxygen atmosphere is disclosed, which circumvents the use of external …

Arynes are employed in the transition-metal-free and mild [2, 3] Stevens rearrangement of
tertiary allylic amines for the synthesis of functionalized homoallylic amines in moderate to …

Azetidines (azacyclobutanes) constitute a well-known class of heterocyclic compounds.
Azetidine scaffold has been discovered in several natural products. Several …

A concise and direct synthetic strategy for the construction of 2-aryliminochromene skeleton
by cascade three-component coupling reaction of arynes, N, S-keteneacetals, and DMF in …