IntelliCage for mice is a rodent home-cage equipped with four corner structures harboring
symmetrical double panels for operant conditioning at each of the two sides, either by …

Despite widespread adoption of tissue clearing techniques in recent years, poor access to
suitable light-sheet fluorescence microscopes remains a major obstacle for biomedical end …

Developmental exposure to ethanol is a leading cause of cognitive, emotional and
behavioral problems, with fetal alcohol spectrum disorder (FASD) affecting more than 1: 100 …

Opioid use disorder is a chronic, relapsing disease associated with persistent changes in
brain plasticity. A common single nucleotide polymorphism (SNP) in the µ-opioid receptor …

Alcohol dependence is characterized by the abnormal release of dopamine in the brain
reward‐related areas. Trace amine‐associated receptor 1 (TAAR1) is a G protein‐coupled …

Background Excessive alcohol consumption leads to serious health problems. Mechanisms
regulating the consumption of alcohol are insufficiently understood. Previous preclinical …

Psilocybin, ketamine, and MDMA are psychoactive compounds that exert behavioral effects
with distinguishable but also overlapping features. The growing interest in using these …

Abstract The three-dimensional (3D) anatomical structure of living organisms is intrinsically
linked to their functions, yet modern life sciences have not fully explored this aspect …

Frontloading is an alcohol drinking pattern where intake is skewed toward the onset of
access. The goal of the current study was to identify brain regions involved in frontloading …

Graphical Summary: Binge-like ethanol drinking engages more regions and NAcc inputs in
female relative to male mice. Left: Comparison of regions with both greater c-Fos expression …