Spinal cord injury (SCI) lesions present diverse challenges for repair strategies.
Anatomically complete injuries require restoration of neural connectivity across lesions …

Spinal interneurons are important facilitators and modulators of motor, sensory, and
autonomic functions in the intact CNS. This heterogeneous population of neurons is now …

The central nervous system is not a static, hard-wired organ. Examples of neuroplasticity,
whether at the level of the synapse, the cell, or within and between circuits, can be found …

While spinal cord injuries (SCIs) result in a vast array of functional deficits, many of which
are life threatening, the majority of SCIs are anatomically incomplete. Spared neural …

The phrenic neuromuscular system consists of the phrenic motor nucleus in the mid-cervical
spinal cord, the phrenic nerve, and the diaphragm muscle. This motor system helps sustain …

The specific roles that different types of neurons play in recovery from injury is poorly
understood. Here, we show that increasing the excitability of ipsilaterally projecting …

Introduction: There have been a wide range of preclinical studies testing cellular therapies to
repair the injured spinal cord, yet they remain a challenge to translate because of …

The study of respiratory plasticity in animal models spans decades. At the bench,
researchers use an array of techniques aimed at harnessing the power of plasticity within …

There is growing appreciation for astrocyte heterogeneity both across and within central
nervous system (CNS) regions, as well as between intact and diseased states. Recent work …

Breathing constantly adapts to environmental, metabolic or behavioral changes by
responding to different sensory information, including afferent feedback from muscles …