Ageing is accompanied by decrements in the size and function of skeletal muscle that
compromise independence and quality of life in older adults. Developing therapeutic …

For centuries, regular exercise has been acknowledged as a potent stimulus to promote,
maintain, and restore healthy functioning of nearly every physiological system of the human …

Age-associated chronic basal inflammation compromises muscle mass and adaptability, but
exercise training may exert an anti-inflammatory effect. This investigation assessed basal …

Skeletal muscle contractile function is impaired in menopause and exercise may mitigate
this decline. We used the 4-vinylcyclohexene diepoxide (VCD) model of menopause to …

Healthspan is the period of our life without major debilitating diseases. In the modern world
where unhealthy lifestyle choices and chronic diseases taper the healthspan, which lead to …

Key points Masters athletes maintain high levels of activity into older age and allow an
examination of the effects of aging dissociated from the effects of increased sedentary …

The cellular causes of the age‐related loss in power output and increased fatigability are
unresolved. We previously observed that the depressive effects of hydrogen (H+)(pH 6.2) …

The Exercise Boom of the 1970's resulted in the adoption of habitual exercise in a significant
portion of the population. Many of these individuals are defying the cultural norms by …

Aging is associated with gradual decline in numerous physiological processes, including a
reduction in metabolic functions and immunological system. The circadian rhythm plays a …

Chemically skinned fibres allow the study of human muscle contractile function in vitro. A
particularly important parameter is specific force (SF), that is, maximal isometric force divided …