Alzheimer's disease: epidemiology and clinical progression

AA Tahami Monfared, MJ Byrnes, LA White… - Neurology and …, 2022 - Springer
Alzheimer's disease (AD) is prevalent throughout the world and is the leading cause of
dementia in older individuals (aged≥ 65 years). To gain a deeper understanding of the …

Modifiable, non-modifiable, and clinical factors associated with progression of Alzheimer's disease

DA Loeffler - Journal of Alzheimer's Disease, 2021 - content.iospress.com
There is an extensive literature relating to factors associated with the development of
Alzheimer's disease (AD), but less is known about factors which may contribute to its …

Genome‐wide association study of rate of cognitive decline in Alzheimer's disease patients identifies novel genes and pathways

R Sherva, A Gross, S Mukherjee… - Alzheimer's & …, 2020 - Wiley Online Library
Introduction Variability exists in the disease trajectories of Alzheimer's disease (AD) patients.
We performed a genome‐wide association study to examine rate of cognitive decline (ROD) …

Progression of Alzheimer's disease: a longitudinal study in Norwegian memory clinics

RS Eldholm, ML Barca, K Persson… - Journal of …, 2018 - content.iospress.com
Background: The course of Alzheimer's disease (AD) varies considerably between
individuals. There is limited evidence on factors important for disease progression …

Predictors of rapid cognitive decline in patients with mild-to-moderate Alzheimer disease: a prospective cohort study with 12-month follow-up performed in memory …

AE Tchalla, JP Clément, I Saulnier… - Dementia and Geriatric …, 2018 - karger.com
Abstract Background/Aims: Alzheimer disease (AD) is particularly devastating, with no cure,
no means of prevention, and no proven way to slow progression. AD is associated with the …

Comparative evaluation of clinical and cerebrospinal fluid biomarker characteristics in rapidly and non-rapidly progressive Alzheimer's disease

JM Herden, P Hermann, I Schmidt, K Dittmar… - Alzheimer's Research & …, 2023 - Springer
Background Rapidly progressive forms of Alzheimer's disease (rpAD) are increasingly
recognized and may have a prevalence of up to 30% of patients among all patients with …

Assessment of need and practice for assistive technology and telecare for people with dementia—The ATTILA (Assistive Technology and Telecare to maintain …

K Forsyth, C Henderson, L Davis… - … Research & Clinical …, 2019 - Wiley Online Library
Introduction The objective of this study was to define current assistive technology and
telecare (ATT) practice for people with dementia living at home. Methods This is a …

Association between peripheral leptin and adiponectin levels and cognitive decline in patients with neurocognitive disorders≥ 65 years

T Gilbert, S Roche, E Blond, JY Bar… - Journal of …, 2018 - content.iospress.com
Background: There is evidence that adipokines have roles in brain functioning and cognitive
decline. Objective: Assess the role of leptin and adiponectin levels in predicting changes in …

Dementia subtypes, cognitive decline and survival among older adults attending a memory clinic in Cape Town, South Africa: a retrospective study

M Ssonko, A Hardy, V Naganathan, S Kalula… - BMC geriatrics, 2023 - Springer
Background There are no published longitudinal studies from Africa of people with dementia
seen in memory clinics. The aim of this study was to determine the proportions of the …

Potential Impact of Slowing Disease Progression in Early Symptomatic Alzheimer's Disease on Patient Quality of Life, Caregiver Time, and Total Societal Costs …

JM Chandler, W Ye, X Mi, EG Doty… - Journal of Alzheimer's …, 2024 - content.iospress.com
Background: Impact of Alzheimer's disease (AD) progression on patient health-related
quality of life (HRQoL), caregiver time, and societal costs is not well characterized in early …