The expression of correctly folded and functional heterologous proteins is important in many
biotechnological production processes, whether it is enzymes, biopharmaceuticals or …

Transfer RNAs have been extensively explored as the molecules that translate the genetic
code into proteins. At this interface of genetics and biochemistry, tRNAs direct the efficiency …

Nonuniform local translation speed dictates diverse protein biogenesis outcomes. To unify
known and uncover unknown principles governing eukaryotic elongation rate, we …

The control of messenger RNA (mRNA) translation has been increasingly recognized as a
key regulatory step for gene control, but clear examples in eukaryotes are still scarce …

Translation is regulated spatiotemporally to direct protein synthesis when and where it is
needed. RNA localization and local translation have been observed in various subcellular …

Converting genetic information into functional proteins is a complex, multi-step process, with
each step being tightly regulated to ensure the accuracy of translation, which is critical to …

Aurora Kinase A (AURKA) is a positive regulator of mitosis with a strict cell cycle-dependent
expression pattern. Recently, novel oncogenic roles of AURKA have been uncovered that …

Despite sustained efforts to treat neurodegenerative diseases, little is known at the
molecular level to understand and generate novel therapeutic approaches for these …

Continued mRNA translation and protein production are critical for various neuronal
functions. In addition to the precise sorting of proteins from cell soma to distant locations …

Protein synthesis is essential to support homeostasis, and thus, must be highly regulated
during cellular response to harmful environments. All stages of translation are susceptible to …