Cellular responses to viral infection in humans: lessons from Epstein-Barr virus
AD Hislop, GS Taylor, D Sauce… - Annu. Rev. Immunol …, 2007 - annualreviews.org
Epstein-Barr virus (EBV) provides a useful model to study cellular immunity to a genetically
stable, persistent human virus. Different sets of proteins expressed during EBV's lytic and …
stable, persistent human virus. Different sets of proteins expressed during EBV's lytic and …
Human cytomegalovirus: clinical aspects, immune regulation, and emerging treatments
MK Gandhi, R Khanna - The Lancet infectious diseases, 2004 - thelancet.com
After initial infection, human cytomegalovirus remains in a persistent state with the host.
Immunity against the virus controls replication, although intermitent viral shedding can still …
Immunity against the virus controls replication, although intermitent viral shedding can still …
Prevention of Epstein-Barr virus–lymphoproliferative disease by molecular monitoring and preemptive rituximab in high-risk patients after allogeneic stem cell …
JWJ van Esser, HGM Niesters… - Blood, The Journal …, 2002 - ashpublications.org
Recipients of a partially T-cell–depleted (TCD) allogeneic stem cell transplantation (allo-
SCT) developing reactivation of Epstein-Barr virus (EBV) with quantified viral DNA levels …
SCT) developing reactivation of Epstein-Barr virus (EBV) with quantified viral DNA levels …
Ex Vivo Profiling of CD8+-T-Cell Responses to Human Cytomegalovirus Reveals Broad and Multispecific Reactivities in Healthy Virus Carriers
R Elkington, S Walker, T Crough, M Menzies… - Journal of …, 2003 - Am Soc Microbiol
Human cytomegalovirus (HCMV) can establish both nonproductive (latent) and productive
(lytic) infections. Many of the proteins expressed during these phases of infection could be …
(lytic) infections. Many of the proteins expressed during these phases of infection could be …
Effective and long-term control of EBV PTLD after transfer of peptide-selected T cells
A Moosmann, I Bigalke, J Tischer… - Blood, The Journal …, 2010 - ashpublications.org
Posttransplantation lymphoproliferative disease (PTLD) associated with Epstein-Barr virus
(EBV) is a life-threatening complication after allogeneic hematopoietic stem cell …
(EBV) is a life-threatening complication after allogeneic hematopoietic stem cell …
Chronic herpesvirus reactivation occurs in aging
RP Stowe, EV Kozlova, DL Yetman, DM Walling… - Experimental …, 2007 - Elsevier
The aged immune system is characterized by clonal expansions of CD8+ T cells of which a
substantial portion are directed against Epstein-Barr virus (EBV) and cytomegalovirus …
substantial portion are directed against Epstein-Barr virus (EBV) and cytomegalovirus …
Epitope-specific Evolution of Human CD8+ T Cell Responses from Primary to Persistent Phases of Epstein-Barr Virus Infection
AD Hislop, NE Annels, NH Gudgeon… - The Journal of …, 2002 - rupress.org
Primary virus infection often elicits a large CD8+ T cell response which subsequently
contracts to a smaller memory T cell pool; the relationship between these two virus-specific …
contracts to a smaller memory T cell pool; the relationship between these two virus-specific …
Progress in EBV vaccines
DG Van Zyl, J Mautner, HJ Delecluse - Frontiers in oncology, 2019 - frontiersin.org
The Epstein-Barr virus (EBV) is a ubiquitous pathogen that imparts a significant burden of
disease on the human population. EBV is the primary cause of infectious mononucleosis …
disease on the human population. EBV is the primary cause of infectious mononucleosis …
EBV-specific CD8+ T cell memory: relationships between epitope specificity, cell phenotype, and immediate effector function
AD Hislop, NH Gudgeon, MFC Callan… - The Journal of …, 2001 - journals.aai.org
EBV infection in humans induces CD8+ T cell memory to viral epitopes derived from both
lytic and latent cycle Ags. We have analyzed the relationship between the phenotype and …
lytic and latent cycle Ags. We have analyzed the relationship between the phenotype and …
MHC II tetramers visualize human CD4+ T cell responses to Epstein–Barr virus infection and demonstrate atypical kinetics of the nuclear antigen EBNA1 response
Virus-specific CD4+ T cells are key orchestrators of host responses to viral infection yet,
compared with their CD8+ T cell counterparts, remain poorly characterized at the single cell …
compared with their CD8+ T cell counterparts, remain poorly characterized at the single cell …