The gut–liver axis and gut microbiota in health and liver disease

CL Hsu, B Schnabl - Nature Reviews Microbiology, 2023 - nature.com
The trillions of microorganisms in the human intestine are important regulators of health, and
disruptions in the gut microbial communities can cause disease. The gut, liver and immune …

Gut microbial metabolites as multi-kingdom intermediates

KA Krautkramer, J Fan, F Bäckhed - Nature Reviews Microbiology, 2021 - nature.com
The gut microbiota contributes to host physiology through the production of a myriad of
metabolites. These metabolites exert their effects within the host as signalling molecules and …

[HTML][HTML] Role of microbiota-derived short-chain fatty acids in cancer development and prevention

R Mirzaei, A Afaghi, S Babakhani, MR Sohrabi… - Biomedicine & …, 2021 - Elsevier
Following cancer, cells in a particular tissue can no longer respond to the factors involved in
controlling cell survival, differentiation, proliferation, and death. In recent years, it has been …

Gut microbiota and human NAFLD: disentangling microbial signatures from metabolic disorders

J Aron-Wisnewsky, C Vigliotti, J Witjes, P Le… - Nature Reviews …, 2020 - nature.com
Gut microbiota dysbiosis has been repeatedly observed in obesity and type 2 diabetes
mellitus, two metabolic diseases strongly intertwined with non-alcoholic fatty liver disease …

Inulin fibre promotes microbiota-derived bile acids and type 2 inflammation

M Arifuzzaman, TH Won, TT Li, H Yano, S Digumarthi… - Nature, 2022 - nature.com
Dietary fibres can exert beneficial anti-inflammatory effects through microbially fermented
short-chain fatty acid metabolites,, although the immunoregulatory roles of most fibre diets …

[HTML][HTML] Gut microbiota impact on the peripheral immune response in non-alcoholic fatty liver disease related hepatocellular carcinoma

J Behary, N Amorim, XT Jiang, A Raposo… - Nature …, 2021 - nature.com
The gut microbiota is reported to modulate the immune response in hepatocellular
carcinoma (HCC). Here, we employ metagenomic and metabolomic studies to characterise …

Cancer and the microbiome—influence of the commensal microbiota on cancer, immune responses, and immunotherapy

V Matson, CS Chervin, TF Gajewski - Gastroenterology, 2021 - Elsevier
The commensal microbiota has been implicated in the regulation of a diverse array of
physiological processes, both within the gastrointestinal tract and at distant tissue sites …

[HTML][HTML] Reuterin in the healthy gut microbiome suppresses colorectal cancer growth through altering redox balance

HN Bell, RJ Rebernick, J Goyert, R Singhal, M Kuljanin… - Cancer cell, 2022 - cell.com
Microbial dysbiosis is a colorectal cancer (CRC) hallmark and contributes to inflammation,
tumor growth, and therapy response. Gut microbes signal via metabolites, but how the …

[HTML][HTML] Soluble dietary fiber, one of the most important nutrients for the gut microbiota

ZW Guan, EZ Yu, Q Feng - Molecules, 2021 - mdpi.com
Dietary fiber is a widely recognized nutrient for human health. Previous studies proved that
dietary fiber has significant implications for gastrointestinal health by regulating the gut …

[HTML][HTML] Gut microbiota modulation: a novel strategy for prevention and treatment of colorectal cancer

W Fong, Q Li, J Yu - Oncogene, 2020 - nature.com
Research about the role of gut microbiome in colorectal cancer (CRC) is a newly emerging
field of study. Gut microbiota modulation, with the aim to reverse established microbial …