Long COVID science, research and policy

Z Al-Aly, H Davis, L McCorkell, L Soares… - Nature Medicine, 2024 - nature.com
Long COVID represents the constellation of post-acute and long-term health effects caused
by SARS-CoV-2 infection; it is a complex, multisystem disorder that can affect nearly every …

Long COVID: a clinical update

T Greenhalgh, M Sivan, A Perlowski, JŽ Nikolich - The Lancet, 2024 - thelancet.com
Summary Post-COVID-19 condition (also known as long COVID) is generally defined as
symptoms persisting for 3 months or more after acute COVID-19. Long COVID can affect …

The neurobiology of SARS-CoV-2 infection

J Meinhardt, S Streit, C Dittmayer, RV Manitius… - Nature Reviews …, 2024 - nature.com
Worldwide, over 694 million people have been infected with SARS-CoV-2, with an estimated
55–60% of those infected developing COVID-19. Since the beginning of the pandemic in …

[HTML][HTML] Long Covid and Impaired Cognition—More Evidence and More Work to Do

Z Al-Aly, CJ Rosen - New England Journal of Medicine, 2024 - Mass Medical Soc
During the early stages of the Covid-19 pandemic, reports emerged that persons who had
been infected with SARS-CoV-2 were having lingering health problems. Such long-term …

[HTML][HTML] Mechanisms of long COVID and the path toward therapeutics

MJ Peluso, SG Deeks - Cell, 2024 - cell.com
Long COVID, a type of post-acute sequelae of severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2)(PASC) defined by medically unexplained symptoms following …

Vortioxetine for the treatment of post-COVID-19 condition: a randomized controlled trial

RS McIntyre, L Phan, ATH Kwan, RB Mansur… - Brain, 2024 - academic.oup.com
Hitherto no therapeutic has received regulatory approval for the treatment of post-COVID-19
condition (PCC). Cognitive deficits, mood symptoms and significant reduction in health …

Solving the puzzle of Long Covid

Z Al-Aly, E Topol - Science, 2024 - science.org
More than 4 years into the global COVID-19 pandemic, widespread infection with severe
acute respiratory syndrome coronavirus 2 (SARSCoV-2) has left millions of people around …

Virology—The next fifty years

EC Holmes, F Krammer, FD Goodrum - Cell, 2024 - cell.com
Virology has made enormous advances in the last 50 years but has never faced such
scrutiny as it does today. Herein, we outline some of the major advances made in virology …

Challenges and opportunities in long COVID research

RE Hamlin, CA Blish - Immunity, 2024 - cell.com
Long COVID (LC) is a condition in which patients do not fully recover from the initial SARS-
CoV-2 infection but rather have persistent or new symptoms for months to years following …

Host–microbe serotonin metabolism

E Nunzi, M Pariano, C Costantini, E Garaci… - Trends in Endocrinology …, 2024 - cell.com
As a result of a long evolutionary history, serotonin plays a variety of physiological roles,
including neurological, cardiovascular, gastrointestinal, and endocrine functions. While …