Radiotherapy and the gut microbiome: facts and fiction

J Liu, C Liu, J Yue - Radiation Oncology, 2021 - Springer
An ever-growing body of evidence has linked the gut microbiome with both the effectiveness
and the toxicity of cancer therapies. Radiotherapy is an effective way to treat tumors …

Chemotherapy-induced intestinal microbiota dysbiosis impairs mucosal homeostasis by modulating toll-like receptor signaling pathways

L Wei, XS Wen, CJ Xian - International journal of molecular sciences, 2021 - mdpi.com
Chemotherapy-induced intestinal mucositis, a painful debilitating condition affecting up to 40–
100% of patients undergoing chemotherapy, can reduce the patients' quality of life, add …

Gut microbiome components predict response to neoadjuvant chemoradiotherapy in patients with locally advanced rectal cancer: a prospective, longitudinal study

Y Yi, L Shen, W Shi, F Xia, H Zhang, Y Wang… - clinical cancer …, 2021 - AACR
Purpose: The gut microbiome is involved in antitumor immunotherapy and chemotherapy
responses; however, evidence-based research on the role of gut microbiome in predicting …

Diet, microbiome, and cancer immunotherapy—A comprehensive review

M Szczyrek, P Bitkowska, P Chunowski, P Czuchryta… - Nutrients, 2021 - mdpi.com
The immune system plays a key role in cancer suppression. Immunotherapy is widely used
as a treatment method in patients with various types of cancer. Immune checkpoint blockade …

Intestinal microbiota: a novel target to improve anti-tumor treatment?

R Villéger, A Lopès, G Carrier, J Veziant… - International journal of …, 2019 - mdpi.com
Recently, preclinical and clinical studies targeting several types of cancer strongly supported
the key role of the gut microbiota in the modulation of host response to anti-tumoral …

Prospective correlation between the patient microbiome with response to and development of immune-mediated adverse effects to immunotherapy in lung cancer

J Chau, M Yadav, B Liu, M Furqan, Q Dai, S Shahi… - BMC cancer, 2021 - Springer
Background Though the gut microbiome has been associated with efficacy of
immunotherapy (ICI) in certain cancers, similar findings have not been identified for …

[HTML][HTML] The role of the gut microbiome in gastrointestinal cancers

Y Mishra, A Ranjan, V Mishra, A Chattaraj… - Cellular …, 2024 - Elsevier
The gut microbiota present in the human digestive system is incredibly varied and is home to
trillions of microorganisms. The gut microbiome is shaped at birth, while numerous genetic …

Inosine, gut microbiota, and cancer immunometabolism

E Samami, E Aleebrahim-Dehkordi… - American Journal …, 2023 - journals.physiology.org
This article briefly reviews cancer immunity and the role of gut microbiota in carcinogenesis,
followed by an understanding of mechanisms by which inosine is involved in cancer …

New insights into the relationship between gut microbiota and radiotherapy for cancer

Z Li, X Ke, D Zuo, Z Wang, F Fang, B Li - Nutrients, 2022 - mdpi.com
Cancer is the second most common cause of death among humans in the world, and the
threat that it presents to human health is becoming more and more serious. The …

Modulating gut microbiota using nanotechnology to increase anticancer efficacy of the treatments

AT Jalil, SN Thabit, ZK Hanan, MQ Alasheqi… - Macromolecular …, 2023 - Springer
Recent clinical and pathological evidence has implicated the gut microbiota as an interplay
for regulating human body homeostasis, influencing conditions ranging from cancer and …