Micellar drug delivery systems based on natural biopolymers
LI Atanase - Polymers, 2021 - mdpi.com
The broad diversity of structures and the presence of numerous functional groups available
for chemical modifications represent an enormous advantage for the development of safe …
for chemical modifications represent an enormous advantage for the development of safe …
Self-assembling peptide-based building blocks in medical applications
Peptides and peptide-conjugates, comprising natural and synthetic building blocks, are an
increasingly popular class of biomaterials. Self-assembled nanostructures based on …
increasingly popular class of biomaterials. Self-assembled nanostructures based on …
Smart pH-sensitive and temporal-controlled polymeric micelles for effective combination therapy of doxorubicin and disulfiram
X Duan, J Xiao, Q Yin, Z Zhang, H Yu, S Mao, Y Li - ACS nano, 2013 - ACS Publications
The combination of a chemotherapeutic drug with a multidrug resistance (MDR) modulator
has emerged as a promising strategy for treating MDR cancer. To ensure two drugs could be …
has emerged as a promising strategy for treating MDR cancer. To ensure two drugs could be …
Peptide-polymer conjugates: from fundamental science to application
JY Shu, B Panganiban, T Xu - Annual review of physical …, 2013 - annualreviews.org
Peptide/protein-polymer conjugates make up a new class of soft matter comprising natural
and synthetic building blocks. They have the potential to combine the advantages of proteins …
and synthetic building blocks. They have the potential to combine the advantages of proteins …
Functional long circulating single walled carbon nanotubes for fluorescent/photoacoustic imaging-guided enhanced phototherapy
Nanotherapeutics have been investigated for years, but only modest survival benefits were
observed clinic. This is partially attributed to the short and rapid elimination of nanodrug after …
observed clinic. This is partially attributed to the short and rapid elimination of nanodrug after …
The anti-tumor efficacy of curcumin when delivered by size/charge-changing multistage polymeric micelles based on amphiphilic poly (β-amino ester) derivates
Y Yu, X Zhang, L Qiu - Biomaterials, 2014 - Elsevier
Modifying positive surface charge and reducing bulk size of nanoparticles has been proven
beneficial to cancer cellular delivery, but meanwhile results in fast clearance and unspecific …
beneficial to cancer cellular delivery, but meanwhile results in fast clearance and unspecific …
CD8+ T-Cell Density Imaging with 64Cu-Labeled Cys-Diabody Informs Immunotherapy Protocols
JW Seo, R Tavaré, LM Mahakian, MT Silvestrini… - Clinical Cancer …, 2018 - AACR
Purpose: Noninvasive and quantitative tracking of CD8+ T cells by PET has emerged as a
potential technique to gauge response to immunotherapy. We apply an anti-CD8 cys …
potential technique to gauge response to immunotherapy. We apply an anti-CD8 cys …
Harnessing the therapeutic potential of biomacromolecules through intracellular delivery of nucleic acids, peptides, and proteins
Biomacromolecules have long been at the leading edge of academic and pharmaceutical
drug development and clinical translation. With the clinical advances of new therapeutics …
drug development and clinical translation. With the clinical advances of new therapeutics …
Positron emission tomography image-guided drug delivery: current status and future perspectives
Positron emission tomography (PET) is an important modality in the field of molecular
imaging, which is gradually impacting patient care by providing safe, fast, and reliable …
imaging, which is gradually impacting patient care by providing safe, fast, and reliable …
Lipid–calcium phosphate nanoparticles for delivery to the lymphatic system and SPECT/CT imaging of lymph node metastases
A lipid/calcium/phosphate (LCP) nanoparticle (NP) formulation (particle diameter∼ 25 nm)
with superior siRNA delivery efficiency was developed and reported previously. Here, we …
with superior siRNA delivery efficiency was developed and reported previously. Here, we …