DNA origami

S Dey, C Fan, KV Gothelf, J Li, C Lin, L Liu… - Nature Reviews …, 2021 - nature.com
Biological materials are self-assembled with near-atomic precision in living cells, whereas
synthetic 3D structures generally lack such precision and controllability. Recently, DNA …

Dynamic DNA nanotechnology: toward functional nanoscale devices

M DeLuca, Z Shi, CE Castro, G Arya - Nanoscale Horizons, 2020 - pubs.rsc.org
Dynamic DNA nanotechnology involves the creation of nanoscale devices made of DNA
whose primary function arises from their ability to undergo controlled motion or …

A rhythmically pulsing leaf-spring DNA-origami nanoengine that drives a passive follower

M Centola, E Poppleton, S Ray, M Centola… - Nature …, 2024 - nature.com
Molecular engineering seeks to create functional entities for modular use in the bottom-up
design of nanoassemblies that can perform complex tasks. Such systems require fuel …

Robotic DNA nanostructures

S Nummelin, B Shen, P Piskunen, Q Liu… - ACS Synthetic …, 2020 - ACS Publications
Over the past decade, DNA nanotechnology has spawned a broad variety of functional
nanostructures tailored toward the enabled state at which applications are coming …

DNA nanotechnology‐based biosensors and therapeutics

L Shen, P Wang, Y Ke - Advanced healthcare materials, 2021 - Wiley Online Library
Over the past few decades, DNA nanotechnology engenders a vast variety of programmable
nanostructures utilizing Watson–Crick base pairing. Due to their precise engineering …

Simulation‐Assisted Localized DNA Logical Circuits for Cancer Biomarkers Detection and Imaging

Q Kou, L Wang, L Zhang, L Ma, S Fu, X Su - Small, 2022 - Wiley Online Library
DNA‐based nanodevices equipped with localized modules have been promising probes for
biomarker detection. Such devices heavily rely on the intramolecular hybridization reaction …

Structural DNA nanotechnology: artificial nanostructures for biomedical research

Y Ke, C Castro, JH Choi - Annual review of biomedical …, 2018 - annualreviews.org
Structural DNA nanotechnology utilizes synthetic or biologic DNA as designer molecules for
the self-assembly of artificial nanostructures. The field is founded upon the specific …

Integrated computer-aided engineering and design for DNA assemblies

CM Huang, A Kucinic, JA Johnson, HJ Su, CE Castro - Nature Materials, 2021 - nature.com
Recently, DNA has been used to make nanodevices for a myriad of applications across
fields including medicine, nanomanufacturing, synthetic biology, biosensing and biophysics …

Programmable multivalent DNA-origami tension probes for reporting cellular traction forces

PK Dutta, Y Zhang, AT Blanchard, C Ge, M Rushdi… - Nano …, 2018 - ACS Publications
Mechanical forces are central to most, if not all, biological processes, including cell
development, immune recognition, and metastasis. Because the cellular machinery …

Storage of mechanical energy in DNA nanorobotics using molecular torsion springs

M Vogt, M Langecker, M Gouder, E Kopperger… - Nature Physics, 2023 - nature.com
DNA nanostructures are increasingly used for the realization of mechanically active
nanodevices and DNA-based nanorobots. A fundamental challenge in this context is the …