The process of bone remodeling is the result of the regulated balance between bone cell
populations, namely bone-forming osteoblasts, bone-resorbing osteoclasts, and the …

Tumor-induced osteomalacia (TIO) is an ultrarare paraneoplastic syndrome due to
overproduction of fibroblast growth factor 23 (FGF23), with profound effects on patient …

Osteoimmunology is a new subject which focuses on the communication between the
immune and the skeletal systems. Both the immune system and bone communicate with …

Abstract Fibroblast growth factor 23 (FGF23) was initially characterized as an important
regulator of phosphate and calcium homeostasis. New research advances demonstrate that …

Patients with chronic kidney disease (CKD) develop increased levels of the phosphate-
regulating hormone, fibroblast growth factor (FGF) 23, that are associated with a higher risk …

Abstracts Bone mainly functions as a supportive framework for the whole body and is the
major regulator of calcium homeostasis and hematopoietic function. Recently, an increasing …

Fibroblast growth factor (FGF) 23 is a phosphaturic hormone whose physiologic actions on
target tissues are mediated by FGF receptors (FGFR) and klotho, which functions as a co …

Highlights•Osteocytes regulate bone formation through a number of interacting signalling
pathways.•Osteocytes regulate bone resorption through controlling osteoclast activity and …

Abstract Fibroblast growth factor 23 (FGF23) is a hormone with a central role in the
regulation of phosphate homeostasis. This regulation is accomplished by the coordinated …

After identification of fibroblast growth factor (FGF) 23 as the pivotal regulator of chronic
serum inorganic phosphate (Pi) levels, the etiology of disorders causing hypophosphatemic …