Radiogenomic analysis of oncological data: a technical survey
M Incoronato, M Aiello, T Infante, C Cavaliere… - International journal of …, 2017 - mdpi.com
In the last few years, biomedical research has been boosted by the technological
development of analytical instrumentation generating a large volume of data. Such …
development of analytical instrumentation generating a large volume of data. Such …
Heart failure: Pilot transcriptomic analysis of cardiac tissue by RNA-sequencing
Background: Despite left ventricular (LV) dysfunction contributing to mortality in chronic heart
failure (HF), the molecular mechanisms of LV failure continues to remain poorly understood …
failure (HF), the molecular mechanisms of LV failure continues to remain poorly understood …
Familial dilated cardiomyopathy: a novel MED9 short isoform identification
Familial dilated cardiomyopathy (DCM) is among the leading indications for heart
transplantation. DCM alters the transcriptomic profile. The alteration or activation/silencing of …
transplantation. DCM alters the transcriptomic profile. The alteration or activation/silencing of …
[HTML][HTML] Down syndrome child with multiple heart diseases: A case report
MW Kong, YJ Li, J Li, ZY Pei, YY Xie… - World Journal of …, 2023 - ncbi.nlm.nih.gov
BACKGROUND Down syndrome, also known as trisomy 21 syndrome, is commonly
associated with congenital heart disease, and can often result in early formation of …
associated with congenital heart disease, and can often result in early formation of …
[HTML][HTML] MiR-145 facilitates proliferation and migration of endothelial progenitor cells and recanalization of arterial thrombosis in cerebral infarction mice via JNK …
R Chen, S Chen, J Liao, X Chen… - International Journal of …, 2015 - ncbi.nlm.nih.gov
Arterial thrombosis in cerebral infarction severely affects patients' lives. Classical treatment
including surgery and medication both had significantly adverse effects, making it necessary …
including surgery and medication both had significantly adverse effects, making it necessary …
整合分析多组学数据筛选疾病靶点的精准医学策略
谢兵兵， 杨亚东， 丁楠， 方向东 - 遗传, 2015 - chinagene.cn
随着高通量测序技术的不断发展与完善, 对于不同层次和类型的生物组学数据的获取及分析方法
也日趋成熟与完善. 基于单组学数据的疾病研究已经发现了诸多新的疾病相关因子 …
也日趋成熟与完善. 基于单组学数据的疾病研究已经发现了诸多新的疾病相关因子 …
BIM and NOXA are mitochondrial effectors of TAF6δ-driven apoptosis
A Delannoy, E Wilhelm, S Eilebrecht… - Cell Death & …, 2018 - nature.com
TAF6δ is a pro-apoptotic splice variant of the RNA polymerase II general transcription factor,
TAF6, that can dictate life vs. death decisions in animal cells. TAF6δ stands out from …
TAF6, that can dictate life vs. death decisions in animal cells. TAF6δ stands out from …
Hif1α and p53 regulated med30, a mediator complex subunit, is involved in regulation of glioblastoma pathogenesis and temozolomide resistance
A Shukla, S Srivastava, J Darokar… - Cellular and Molecular …, 2021 - Springer
Glioblastoma (GBM) is the most common, malignant, and aggressive form of glial cell cancer
with unfavorable clinical outcomes. It is believed that a better understanding of the …
with unfavorable clinical outcomes. It is believed that a better understanding of the …
Application of quantitative trait locus mapping and transcriptomics to studies of the senescence-accelerated phenotype in rats
EE Korbolina, NI Ershov, LO Bryzgalov, NG Kolosova - BMC genomics, 2014 - Springer
Background Etiology of complex disorders, such as cataract and neurodegenerative
diseases including age-related macular degeneration (AMD), remains poorly understood …
diseases including age-related macular degeneration (AMD), remains poorly understood …
Splicing regulators in endothelial cell differentiation
Aims Alternative splicing represents a key mechanism of gene regulation. Despite its role in
regulating cell pluripotency and differentiation being well known, the underlining …
regulating cell pluripotency and differentiation being well known, the underlining …