In recent years, a number of studies focused on the role of epigenetics, including DNA
methylation, in spermatogenesis and male infertility. We aimed to provide an overview of the …

Infertility affects approximately 15% of the couples wanting to conceive. In 30− 40% of the
cases the aetiology of male infertility remains unknown and is called idiopathic male …

Nutrition is a modifiable key factor that is able to interact with both the genome and
epigenome to influence human health and fertility. In particular, specific genetic variants can …

BACKGROUND The many manipulations and processes used in ART coincide with the
timing of epigenetic reprogramming and imprinting during female gametogenesis and pre …

Infertility affects one in six couples worldwide, and fertility continues to deteriorate globally,
partly owing to a decline in semen quality. Sperm analysis has a central role in diagnosing …

ABSTRACT A central question in ecology and evolution is to understand why sexual
selection varies so much in strength across taxa; it has long been known that ecological …

Male infertility is a multifactorial condition influenced by epigenetic regulation, oxidative
stress, and mitochondrial dysfunction. Oxidative stress-induced damage leads to epigenetic …

Recent studies have indicated that epigenetic alterations are critical for normal function and
development of spermatozoa during the fertilization process. This review will focus on the …

Infertility is an often devastating diagnosis encountered by around one in six couples who
are trying to conceive. Moving away from the long-held belief that infertility is primarily a …

Background Conflicting results regarding alterations to sperm DNA methylation in cases of
spermatogenesis defects, male infertility and poor developmental outcomes have been …