Cadherins are the principal adhesion proteins at intercellular junctions and function as the
biochemical Velcro that binds cells together. Besides this mechanical function, cadherin …

The ability of cells to organize into multicellular structures in precise patterns requires that
they" recognize" one another with high specificity. We discuss recent progress in …

Cadherins are a superfamily of cell surface glycoproteins whose ectodomains contain
multiple repeats of β-sandwich extracellular cadherin (EC) domains that adopt a similar fold …

The circulating, adipocyte-secreted hormone adiponectin (APN) exerts protective effects on
the heart under stress conditions. The receptors binding APN to cardiac tissue, however …

Classical cadherin cell-cell adhesion proteins play key morphogenetic roles during
development and are essential for maintaining tissue integrity in multicellular organisms …

Cadherins are Ca2+-dependent cell-cell adhesion molecules that play critical roles in
animal morphogenesis. Various cadherin-related molecules have also been identified …

Genetic and environmental components as well as their interaction contribute to the risk of
schizophrenia, making it highly relevant to include environmental factors in genetic studies …

Crystal structures of classical cadherins have revealed two dimeric configurations. In the
first, N-terminal β-strands of EC1 domains' swap'between partner molecules. The second …

The organization and coordination of fish schools provide a valuable model to investigate
the genetic architecture of affiliative behaviours and dissect the mechanisms underlying …

Activity in the healthy brain relies on a concerted interplay of excitation (E) and inhibition (I)
via balanced synaptic communication between glutamatergic and GABAergic neurons. A …