Recent advances on application nanomagnetic recoverable catalysts for synthesis of 1, 4-dihydropyridine (DHPs)

J Hou, M Kazemi - Research on Chemical Intermediates, 2024 - Springer
Abstract In recent years, 1, 4-dihydropyridine derivatives (DHPs) have attracted the attention
of chemists because DHPs derivatives have many biological properties and are present in …

Construction of 1, 4-dihydropyridines: The evolution of C4 source

S Song, Y Wang, F Yu - Topics in Current Chemistry, 2023 - Springer
The field of cascade cyclization for the construction of 1, 4-dihydropyridines (1, 4-DHPs) has
been continuously expanding during the last decades because of their broad-spectrum …

Copper‐Catalyzed Oxidative [1+2+1+2] Cascade Cyclization of N,N‐Dimethyl Enaminones with Benzylamines: A Facile Access to Functionalized 1,4 …

Y Sun, Z Chai, D Liu, M Zhang, L Chen… - … A European Journal, 2023 - Wiley Online Library
Using benzylamines as the C4 source of 1, 4‐dihydropyridines (1, 4‐DHPs), a Cu‐catalyzed
oxidative [1+ 2+ 1+ 2] cascade cyclization for the synthesis of 1, 4‐DHPs was firstly …

An Oxidative [3+2+1] Cyclization of Enaminones and N‐Alkenyl‐2‐pyrrolidinone: Access to Polysubstituted 4‐Alkylated 1,4‐dihydropyridines

Z Chai, L Chen, Z Liu, Y Sun, D Liu… - Advanced Synthesis …, 2023 - Wiley Online Library
Abstract An oxidative [3+ 2+ 1] cyclization of enaminones and N‐alkenyl‐2‐pyrrolidinone is
described for the synthesis of 4‐alkylated 1, 4‐dihydropyridines (1, 4‐DHPs). By using …

Design, Synthesis, and Biological Evaluation of 1, 4-Dihydropyridine–Indole as a Potential Antidiabetic Agent via GLUT4 Translocation Stimulation

S Katiyar, S Ahmad, A Kumar, A Ansari… - Journal of Medicinal …, 2024 - ACS Publications
In the quest for the discovery of antidiabetic compounds, a series of 27 1, 4-dihydropyridine–
indole derivatives were synthesized using a diversity approach. These compounds were …

The mystery of titan hunter: Rationalized striking of the MAPK pathway via Newly synthesized 6‐Indolylpyridone‐3‐Carbonitrile derivatives

MM Saleh, T El-Moselhy, E El-Bastawissy… - European Journal of …, 2023 - Elsevier
MAPK pathway sparkles with RTK activation, passes through subsequent downstream RAS-
RAF-MEK-ERK signaling cascades, with consequent direct and indirect CDK4/6 signaling …

A sustainable protocol for the synthesis of highly substituted dihydropyridines using Cu5 (PW10V2O40) 2 as an efficacy and reusable heterogeneous catalyst

CV Subrahmanyam, BS Rao, BS Kumar… - Inorganic Chemistry …, 2023 - Elsevier
In this investigation, an efficient and eco-friendly novel copper loaded hetero-poly-acid [Cu 5
(PW 10 V 2 O 40) 2] nano-catalystic complex was designed and its catalytic performance …

Synthesis and application of an effective magnetic catalyst immobilized copper oxide for the one-pot ultrasound-assisted synthesis of 1, 4-dihydropyridines

K Dolatyari, MM Khodaei - Journal of Organometallic Chemistry, 2024 - Elsevier
In this study, Fe 3 O 4 was modified with a biocompatible carbohydrate D-(+)-ribonic γ-
lactone (RL) followed by immobilization with CuO nanoparticles (CuO NPs) to produce Fe 3 …

Synthesis and biological assessment of novel 4H-chromene-3-carbonitrile derivatives as tyrosinase inhibitors

M Azimi, Z Najafi, A Bahmani, G Chehardoli, A Iraji - BMC chemistry, 2024 - Springer
Excessive activity of the tyrosinase enzyme during melanogenesis results in
hyperpigmentation in the skin. To address this issue, there is a need to develop effective …

Design, Synthesis, and Screening for Anticancer and Antimicrobial Activities of New Dihydropyridine‐Anchored Pyrazole and 1, 2, 3‐Triazole Hybrids

K Chevula, N Patnam, P Chennamsetti… - …, 2024 - Wiley Online Library
Two new libraries of diethyl and dimethyl dihydropyridines‐based pyrazole and 1, 2, 3‐
triazole hybrids (7a–g and 7h–n) were synthesized via a series of reactions involving click …