Non-coding RNAs in glioma

R Rynkeviciene, J Simiene, E Strainiene… - Cancers, 2018 - mdpi.com
Glioma is the most aggressive brain tumor of the central nervous system. The ability of
glioma cells to migrate, rapidly diffuse and invade normal adjacent tissue, their sustained …

The multifaceted role of aldehyde dehydrogenases in prostate cancer stem cells

J Püschel, A Dubrovska, I Gorodetska - Cancers, 2021 - mdpi.com
Simple Summary Cancer stem cells (CSCs) are an engine of tumor progression and a
source of tumor therapy resistance and regrowth after treatment. Modern conventional …

[HTML][HTML] Long non-coding RNA DLEU2 promotes the progression of esophageal cancer through miR-30e-5p/E2F7 axis

T Lu, R Wang, H Cai, Y Cui - Biomedicine & Pharmacotherapy, 2020 - Elsevier
Background Emerging evidences have proven the important roles of lncRNAs in
tumorigenesis and cancer biology. However, the function of lncRNA DLEU2 in the …

MicroRNA-150 suppresses epithelial-mesenchymal transition, invasion, and metastasis in prostate cancer through the TRPM4-mediated β-catenin signaling pathway

X Hong, JJ Yu - American Journal of Physiology-Cell …, 2019 - journals.physiology.org
Prostate cancer (PCa) remains one of the leading causes of cancer-related deaths among
males. The aim of the current study was to investigate the ability of microRNA-150 (miR-150) …

HIV-associated cancer biomarkers: a requirement for early diagnosis

Z Dlamini, M Mbele, TJ Makhafola, R Hull… - International Journal of …, 2021 - mdpi.com
Globally, HIV/AIDS and cancer are increasingly public health problems and continue to exist
as comorbidities. The sub-Saharan African region has the largest number of HIV infections …

Withaferin A mediated changes of miRNA expression in breast cancer‐derived mammospheres

KS Prajapati, M Shuaib, S Gupta… - Molecular …, 2022 - Wiley Online Library
Breast cancer is a heterogeneous disease consisting of atypical cell populations that share
stem cell‐like characteristics associated with therapeutic resistance, disease relapse, and …

miR-548x and miR-4698 controlled cell proliferation by affecting the PI3K/AKT signaling pathway in Glioblastoma cell lines

MR Kalhori, E Arefian, F Fallah Atanaki, K Kavousi… - Scientific reports, 2020 - nature.com
Glioblastoma multiforme (GBM) is the most aggressive and prevalent form of brain tumor
cancers that originate from glial cells. This study proposed to investigate the effect of miR …

Natural steroidal lactone induces G1/S phase cell cycle arrest and intrinsic apoptotic pathway by up-regulating tumor suppressive miRNA in triple-negative breast …

M Shuaib, KS Prajapati, S Gupta, S Kumar - Metabolites, 2022 - mdpi.com
Triple-negative breast cancer (TNBC) is an aggressive subtype of breast cancer with
minimal treatment options. In the present work, Withaferin A (WA), a natural steroidal lactone …

[HTML][HTML] Screening and validation of novel serum panel of microRNA in stratification of prostate cancer

A Manoj, MK Ahmad, G Prasad, D Kumar, AA Mahdi… - Prostate …, 2023 - Elsevier
Background Owing to the heterogeneous nature of prostate cancer (PCa) and errors in the
characterization of the disease, researchers have been trying to unveil molecular …

Withaniasomnifera phytochemicals possess SARS-CoV-2 RdRp and human TMPRSS2 protein binding potential

KS Prajapati, AK Singh, PP Kushwaha, M Shuaib… - Vegetos, 2023 - Springer
Abstract Coronavirus disease-19 (COVID-19) pandemic caused by severe acute respiratory
syndrome-coronavirus-2 (SARS-CoV-2) has infected approximately 26 million people and …