Aflatoxin B1: A review on metabolism, toxicity, occurrence in food, occupational exposure, and detoxification methods

BR Rushing, MI Selim - Food and chemical toxicology, 2019 - Elsevier
Aflatoxins are a class of carcinogenic mycotoxins produced by Aspergillus fungi and are
known to contaminate a large portion of the world's food supply. Aflatoxin B1 (AFB1) is the …

Aflatoxin B1 and M1: Biological properties and their involvement in cancer development

S Marchese, A Polo, A Ariano, S Velotto, S Costantini… - Toxins, 2018 - mdpi.com
Aflatoxins are fungal metabolites found in feeds and foods. When the ruminants eat
feedstuffs containing Aflatoxin B1 (AFB1), this toxin is metabolized and Aflatoxin M1 (AFM1) …

Aflatoxin B1: Metabolism, toxicology, and its involvement in oxidative stress and cancer development

W Cao, P Yu, KP Yang, D Cao - Toxicology Mechanisms and …, 2022 - Taylor & Francis
Aflatoxins are a class of carcinogenic mycotoxins produced by Aspergillus fungi, which are
widely distributed in nature. Aflatoxin B1 (AFB1) is the most toxic of these compounds and its …

Chemical risk factors of primary liver cancer: an update

A Barsouk, KC Thandra, K Saginala… - Hepatic Medicine …, 2021 - Taylor & Francis
Primary liver cancer has the sixth highest incidence and fourth highest cancer mortality
worldwide. Hepatitis B is the leading cause of liver cancer, though its incidence is …

The aflatoxin situation in Africa: Systematic literature review

N Meijer, G Kleter, M de Nijs, ML Rau… - … Reviews in Food …, 2021 - Wiley Online Library
Contamination of African staple foods is a major issue for human and animal health,
nutrition, and trade. This review aimed to collect and synthesize the available evidence on …

[HTML][HTML] Non‑infective occupational risk factors for hepatocellular carcinoma: A review

C Ledda, C Loreto, C Zammit… - Molecular …, 2017 - spandidos-publications.com
Liver cancer is the second leading worldwide cause of cancer‑associated mortalities.
Hepatocellular carcinoma, which accounts for the majority of liver tumors, ranks fifth among …

Mycotoxin contamination in the Arab world: Highlighting the main knowledge gaps and the current legislation

MF Abdallah, M Gado, D Abdelsadek, F Zahran… - Mycotoxin …, 2024 - Springer
Since the discovery of aflatoxins in the 1960s, knowledge in the mycotoxin research field
has increased dramatically. Hundreds of review articles have been published summarizing …

Assessment of workers' exposure to aflatoxin B1 in a Portuguese waste industry

S Viegas, L Veiga, P Figueiredo… - Annals of …, 2015 - academic.oup.com
Aflatoxin B1 (AFB1) is considered by different International Agencies as a genotoxic and
potent hepatocarcinogen. However, despite the fact that the fungi producing this compound …

[HTML][HTML] Hepatocellular carcinoma and the risk of occupational exposure

V Rapisarda, C Loreto, M Malaguarnera… - World journal of …, 2016 - ncbi.nlm.nih.gov
Hepatocellular carcinoma (HCC) is the most common type of liver cancer. The main risk
factors for HCC are alcoholism, hepatitis B virus, hepatitis C virus, nonalcoholic …

Occupational exposure to aflatoxins and health outcomes: a review

RN Wangia, L Tang, JS Wang - Journal of Environmental Science …, 2019 - Taylor & Francis
Aflatoxins [AFs] are secondary metabolites of the fungus species Aspergillus spp. Both
animal and epidemiological studies provided sufficient evidence on the carcinogenic …