A comprehensive and authoritative guide to neurologic disease in large domestic animals,
world-wide. The newly revised Third Edition of Large Animal Neurology delivers a practical …

Genetic variants underlying reduced male reproductive performance have been identified in
humans and model organisms, most of them compromising semen quality. Occasionally …

Motivation: The prioritization and identification of disease-causing mutations is one of the
most significant challenges in medical genomics. Currently available methods address this …

Charcot-Marie-Tooth disease (CMT) represents a group of neurodegenerative disorders
typically characterised by demyelination (CMT1) or distal axon degeneration (CMT2) of …

Background Haplotypes with reduced or missing homozygosity may harbor deleterious
alleles that compromise juvenile survival. A scan for homozygous haplotype deficiency …

Background Inherited developmental diseases can cause severe animal welfare and
economic problems in dairy cattle. The use of a small number of bulls for artificial …

Analysis of genomic data is increasingly becoming part of the livestock industry. Therefore,
the routine collection of genomic information would be an invaluable resource for effective …

Vertebral body infection and epidural spinal abscesses occur regularly in ruminants,
occurring in both young and adult animals. These conditions are seen more commonly in …

Mutations in> 30 genes are known to result in impairment of the adaptive immune system,
causing a group of disorders collectively known as SCID. SCID disorders are split into …

Background The membrane protein CD46, a ubiquitous cell surface pathogen receptor, can
bind Streptococcus to trigger cell autophagy, which is a critical step in the control of infection …