[HTML][HTML] Physiology and pathophysiology of cyclooxygenase-2 and prostaglandin E2 in the kidney

R Nørregaard, TH Kwon, J Frøkiær - Kidney research and clinical practice, 2015 - Elsevier
The cyclooxygenase (COX) enzyme system is the major pathway catalyzing the conversion
of arachidonic acid into prostaglandins (PGs). PGs are lipid mediators implicated in a variety …

Targeting inflammation and oxidative stress as a therapy for ischemic kidney injury

NV Andrianova, DB Zorov, EY Plotnikov - Biochemistry (Moscow), 2020 - Springer
Inflammation and oxidative stress are the main pathological processes that accompany
ischemic injury of kidneys and other organs. Based on this, these factors are often chosen as …

Potential drugs for the treatment of Alzheimer's disease

TG Montero-Cosme, LI Pascual-Mathey… - Pharmacological …, 2023 - Springer
It is well known that amyloid precursor protein (APP), the enzyme β-secretase 1 (BACE1),
cyclooxygenase 2 (COX-2), nicastrin (NCT), and hyperphosphorylated tau protein (p-tau) …

[HTML][HTML] Cyclooxygenase biology in renal function-literature review

M Goetz Moro, PK Vargas Sánchez… - Revista Colombiana …, 2017 - scielo.org.co
The cyclooxygenase (COX) exists in two main isoforms, COX-1 and COX-2, which are
present in the renal system to ensure its homeostasis. However, in different clinical …

The investigation of the protective effects of nimesulide on experimental testicular ischemia-reperfusion injury in rats

EC Polat, AS Bozkurt, FK Cimen, M Gulaboglu… - Revista internacional de …, 2020 - Elsevier
Introduction and objectives Testicular ischemia/reperfusion (I/R) injury develops after torsion
and following detorsion of the testis. Reactive oxygen species were produced and oxidative …

Biología de la ciclooxigenasa en la función renal–Revisión de la literatura

MG Moro, PKV Sanchez, AC Lupepsa… - Revista …, 2017 - revistanefrologia.org
La cidooxigenasa existe en dos isoformas principales: COX-1 y COX-2, estas se encuentran
presentes en el sistema renal como parte de su homeostasis. Sin embargo, en algunas …

Effects of nitroglycerine on renal ischemia-reperfusion injury in adult male rats

F Ahmadi, S Hajihashemi, A Rahbari… - Drug …, 2019 - thieme-connect.com
Background Ischemia-reperfusion (IR) leads to acute kidney injury (AKI). The present study
investigated the effects of nitroglycerine (NG) on improving renal dysfunctions caused by IR …

Воспаление и окислительный стресс как мишени для терапии ишемического повреждения почек

НВ Андрианова, ДБ Зоров, ЕЮ Плотников - Биохимия, 2020 - elibrary.ru
Воспаление и окислительный стресс являются основными патологическими
процессами, сопровождающими ишемическое повреждение почек и других органов. В …

[PDF][PDF] Modulatory role of nimesulide, caffeic acid and their combination against immunologically induced mouse model of chronic fatigue syndrome.

P Nain, B Singh, J Kaur - Exploratory Animal & Medical …, 2022 - animalmedicalresearch.org
Chronic Fatigue Syndrome (CFS) is a complex, debilitating illness characterized by
persistent and relapsing fatigue that does not improve with rest. This study aimed to explore …

The effect of nanomicellar curcuminoids on renal ischemia/reperfusion injury and the expressions of COX-2 and Na+/K+-ATPase in rat's kidney

Z Karimi, R Soukhaklari, L Malekmakan… - Physiology and …, 2022 - ppj.phypha.ir
Introduction ylation is inhibited due to the lack of oxygen. This phenomenon impairs ATP
synthesis and reduces the activity of energy-dependent pumps, which can lead to cell death …