The CB2 receptor and its role as a regulator of inflammation
C Turcotte, MR Blanchet, M Laviolette… - Cellular and Molecular …, 2016 - Springer
The CB 2 receptor is the peripheral receptor for cannabinoids. It is mainly expressed in
immune tissues, highlighting the possibility that the endocannabinoid system has an …
immune tissues, highlighting the possibility that the endocannabinoid system has an …
Psychological stress in early life as a predisposing factor for the development of chronic pain: clinical and preclinical evidence and neurobiological mechanisms
A wealth of research over the past 2 decades has expanded our understanding of the impact
of early‐life adversity on physiological function and, consequently, health and wellbeing in …
of early‐life adversity on physiological function and, consequently, health and wellbeing in …
Cannabinoid type 2 receptors mediate a cell type-specific plasticity in the hippocampus
AV Stempel, A Stumpf, HY Zhang, T Özdoğan… - Neuron, 2016 - cell.com
Endocannabinoids (eCBs) exert major control over neuronal activity by activating
cannabinoid receptors (CBRs). The functionality of the eCB system is primarily ascribed to …
cannabinoid receptors (CBRs). The functionality of the eCB system is primarily ascribed to …
To predict, prevent, and manage post-traumatic stress disorder (PTSD): a review of pathophysiology, treatment, and biomarkers
Post-traumatic stress disorder (PTSD) can become a chronic and severely disabling
condition resulting in a reduced quality of life and increased economic burden. The disorder …
condition resulting in a reduced quality of life and increased economic burden. The disorder …
Cannabis and adolescent brain development
Heavy cannabis use has been frequently associated with increased rates of mental illness
and cognitive impairment, particularly amongst adolescent users. However, the …
and cognitive impairment, particularly amongst adolescent users. However, the …
New insights and potential therapeutic targeting of CB2 cannabinoid receptors in CNS disorders
The endocannabinoid system (ECS) is ubiquitous in most human tissues, and involved in
the regulation of mental health. Consequently, its dysregulation is associated with …
the regulation of mental health. Consequently, its dysregulation is associated with …
Cannabinoid receptors CB1 and CB2 form functional heteromers in brain
L Callén, E Moreno, P Barroso-Chinea… - Journal of Biological …, 2012 - ASBMB
Exploring the role of cannabinoid CB 2 receptors in the brain, we present evidence of CB 2
receptor molecular and functional interaction with cannabinoid CB 1 receptors. Using …
receptor molecular and functional interaction with cannabinoid CB 1 receptors. Using …
Species differences in cannabinoid receptor 2 (CNR2 gene): identification of novel human and rodent CB2 isoforms, differential tissue expression and regulation by …
Cannabinoids, endocannabinoids and marijuana activate two well‐characterized
cannabinoid receptors (CB‐Rs), CB1‐Rs and CB2‐Rs. The expression of CB1‐Rs in the …
cannabinoid receptors (CB‐Rs), CB1‐Rs and CB2‐Rs. The expression of CB1‐Rs in the …
Adolescent cannabis use and psychosis: epidemiology and neurodevelopmental models
Cannabis is one of the most widely used illicit drugs among adolescents, and most users
first experiment with it in adolescence. Adolescence is a critical phase for brain …
first experiment with it in adolescence. Adolescence is a critical phase for brain …
Beyond sex differences: new approaches for thinking about variation in brain structure and function
D Joel, A Fausto-Sterling - Philosophical Transactions of …, 2016 - royalsocietypublishing.org
In the study of variation in brain structure and function that might relate to sex and gender,
language matters because it frames our research questions and methods. In this article, we …
language matters because it frames our research questions and methods. In this article, we …