[HTML][HTML] From Crypts to Cancer: A Holistic Perspective on Colorectal Carcinogenesis and Therapeutic Strategies

E Gharib, GA Robichaud - International journal of molecular sciences, 2024 - mdpi.com
Colorectal cancer (CRC) represents a significant global health burden, with high incidence
and mortality rates worldwide. Recent progress in research highlights the distinct clinical …

Metabolite-sensing GPCRs in rheumatoid arthritis

X Yang, W Zhang, L Wang, Y Zhao, W Wei - Trends in Pharmacological …, 2024 - cell.com
Persistent inflammation in damaged joints results in metabolic dysregulation of the synovial
microenvironment, causing pathogenic alteration of cell activity in rheumatoid arthritis (RA) …

Potential of the Novel Slot Blot Method with a PVDF Membrane for Protein Identification and Quantification in Kampo Medicines

T Takata, T Masauji, Y Motoo - Membranes, 2023 - mdpi.com
Kampo is a Japanese traditional medicine modified from traditional Chinese medicine.
Kampo medicines contain various traditional crude drugs with unknown compositions due to …

Glycolysis, a driving force of rheumatoid arthritis

P Gan, H Wu, Y Zhu, Y Shu, Y Wei - International Immunopharmacology, 2024 - Elsevier
Resident synoviocytes and synovial microvasculature, together with immune cells from
circulation, contribute to pannus formation, the main pathological feature of rheumatoid …

Network medicine based approach for identifying the type 2 diabetes, osteoarthritis and triple negative breast cancer interactome: Finding the hub of hub genes

IA Durrani, P John, A Bhatti, JS Khan - Heliyon, 2024 - cell.com
The increasing prevalence of multi-morbidities, particularly the incidence of breast cancer in
diabetic/osteoarthritic patients emphasize on the need for exploring the underlying …

Experimental and computational investigation of the kinetic evolution of the glutaminolysis pathway and its interplay with the glycolysis pathway

Z Mirveis, N Patil, HJ Byrne - FEBS Open Bio, 2024 - Wiley Online Library
Exploring cellular responses necessitates studying real‐time metabolic pathway kinetics,
considering the adaptable nature of cells. Glycolysis and glutaminolysis are interconnected …

Dual inhibitor targets fibroblast metabolism in RA

J McHugh - Nature Reviews Rheumatology, 2023 - nature.com
Dual inhibitor targets fibroblast metabolism in RA | Nature Reviews Rheumatology Skip to main
content Thank you for visiting nature.com. You are using a browser version with limited support …

[图书][B] Adipokines and cell metabolism in early rheumatoid arthritis

G Vasileiadis - 2024 - gupea.ub.gu.se
This thesis aimed to investigate the role of adipokines as adiponectin, leptin, and resistin, as
well as cell metabolism in rheumatoid arthritis (RA). We assessed whether these adipokines …