Molecular recognition reagents are key tools for understanding biological processes and are
used universally by scientists to study protein expression, localisation and interactions …

Biophysics experiments performed at single-molecule resolution provide exceptional insight
into the structural details and dynamic behavior of biological systems. However, extracting …

Single-molecule techniques are powerful tools to investigate the structure and dynamics of
macromolecular complexes; however, data quality can suffer because of weak specific …

A cell membrane can be considered a liquid-phase plane in which lipids and proteins
theoretically are free to diffuse. Numerous reports, however, describe retarded diffusion of …

Plant plasma-membrane (PM) proteins are involved in several vital processes, such as
detection of pathogens, solute transport, and cellular signaling. For these proteins to function …

Recent experimental and theoretical studies of photoluminescence intermittency (PI) or
“blinking” exhibited by single core/shell quantum dots and single organic luminophores are …

Electron multiplication charge-coupled devices (EMCCD) are widely used for photon
counting experiments and measurements of low intensity light sources, and are extensively …

Our current understanding of epidermal growth factor receptor (EGFR) autoinhibition is
based on X-ray structural data of monomer and dimer receptor fragments and does not …

The organization of the plasma membrane is both highly complex and highly dynamic. One
manifestation of this dynamic complexity is the lateral mobility of proteins within the plane of …

Tracking subcellular structures as well as viral structures displayed asparticles' in
fluorescence microscopy images yields quantitative information on the underlying dynamical …