Factors determining phage stability/activity: challenges in practical phage application

E Jończyk-Matysiak, N Łodej, D Kula… - Expert review of anti …, 2019 - Taylor & Francis
Introduction: Phages consist of nucleic acids and proteins that may lose their activity under
different physico-chemical conditions. The production process of phage formulations may …

Interactions of bacteriophages with animal and human organisms—safety issues in the light of phage therapy

M Podlacha, Ł Grabowski… - International journal of …, 2021 - mdpi.com
Bacteriophages are viruses infecting bacterial cells. Since there is a lack of specific
receptors for bacteriophages on eukaryotic cells, these viruses were for a long time …

Long-read metagenomic sequencing reveals shifts in associations of antibiotic resistance genes with mobile genetic elements from sewage to activated sludge

D Dai, C Brown, H Bürgmann, DGJ Larsson, I Nambi… - Microbiome, 2022 - Springer
Background There is concern that the microbially rich activated sludge environment of
wastewater treatment plants (WWTPs) may contribute to the dissemination of antibiotic …

Bacteriophage and endolysin engineering for biocontrol of food pathogens/pathogens in the food: recent advances and future trends

C Lee, H Kim, S Ryu - CritiCal reviews in Food sCienCe and …, 2023 - Taylor & Francis
Despite advances in modern technologies, various foodborne outbreaks have continuously
threatened the food safety. The overuse of and abuse/misuse of antibiotics have escalated …

[HTML][HTML] Efficacy and safety of phage therapy against Salmonella enterica serovars Typhimurium and Enteritidis estimated by using a battery of in vitro tests and the …

K Kosznik-Kwaśnicka, M Stasiłojć, Ł Grabowski… - Microbiological …, 2022 - Elsevier
In light of spreading antibiotic resistance among pathogenic bacteria, the development of
novel approaches to combat such microorganisms is crucial. Salmonella enterica is …

Flagellotropic bacteriophages: opportunities and challenges for antimicrobial applications

NC Esteves, BE Scharf - International Journal of Molecular Sciences, 2022 - mdpi.com
Bacteriophages (phages) are the most abundant biological entities in the biosphere. As
viruses that solely infect bacteria, phages have myriad healthcare and agricultural …

Isolation, characterization and in vivo efficacy of Escherichia phage myPSH1131

P Manohar, AJ Tamhankar, CS Lundborg, N Ramesh - PloS one, 2018 - journals.plos.org
Phage therapy is the use of lytic bacteriophages to cure infections caused by bacteria. The
aim of this study is to isolate and to characterize the bacteriophages against Escherichia coli …

Characterization of a bacteriophage, vB_Eco4M-7, that effectively infects many Escherichia coli O157 strains

A Necel, S Bloch, B Nejman-Faleńczyk, M Grabski… - Scientific reports, 2020 - nature.com
The characterization of a recently isolated bacteriophage, vB_Eco4M-7, which effectively
infects many, though not all, Escherichia coli O157 strains, is presented. The genome of this …

A new pipeline for designing phage cocktails based on phage-bacteria infection networks

F Molina, A Simancas, M Ramírez, R Tabla… - Frontiers in …, 2021 - frontiersin.org
In recent years, the spread of antibiotic-resistant bacteria and efforts to preserve food
microbiota have induced renewed interest in phage therapy. Phage cocktails, instead of a …

Advanced strategies to overcome the challenges of bacteriophage-based antimicrobial treatments in food and agricultural systems

S Liu, SY Quek, K Huang - Critical Reviews in Food Science and …, 2024 - Taylor & Francis
Bacteriophages (phages), highly prevalent in aquatic and terrestrial environments, have
emerged as novel antimicrobial agents in food and agricultural systems. Owing to their …