Curcumin formulations for better bioavailability: what we learned from clinical trials thus far?

M Hegde, S Girisa, B BharathwajChetty, R Vishwa… - ACS …, 2023 - ACS Publications
Curcumin has been credited with a wide spectrum of pharmacological properties for the
prevention and treatment of several chronic diseases such as arthritis, autoimmune …

Role of turmeric and curcumin in prevention and treatment of chronic diseases: Lessons learned from clinical trials

AB Kunnumakkara, M Hegde, D Parama… - ACS Pharmacology & …, 2023 - ACS Publications
Turmeric (Curcuma longa) has been used for thousands of years for the prevention and
treatment of various chronic diseases. Curcumin is just one of> 200 ingredients in turmeric …

Anti-cancer effects of dietary polyphenols via ROS-mediated pathway with their modulation of microRNAs

Y Yoshioka, T Ohishi, Y Nakamura, R Fukutomi… - Molecules, 2022 - mdpi.com
Consumption of coffee, tea, wine, curry, and soybeans has been linked to a lower risk of
cancer in epidemiological studies. Several cell-based and animal studies have shown that …

Daily Lactobacillus probiotic versus placebo in COVID-19-exposed household contacts (PROTECT-EHC): a randomized clinical trial

PE Wischmeyer, H Tang, Y Ren, L Bohannon… - MedRxiv, 2022 - medrxiv.org
STRUCTURED ABSTRACT Importance The COVID-19 pandemic continues to pose
unprecedented challenges to worldwide health. While vaccines are effective, supplemental …

Melanoma Cellular Signaling Transduction Pathways Targeted by Polyphenols Action Mechanisms

E Isacescu, P Chiroi, O Zanoaga, A Nutu, L Budisan… - Antioxidants, 2023 - mdpi.com
Melanoma is the most aggressive type of skin cancer. Although different anti-melanoma
treatments are available, their efficacy is still improvable, and the number of deaths …

Efficacy of probiotic treatment as post-exposure prophylaxis for COVID-19: A double-blind, Placebo-Controlled Randomized trial

PE Wischmeyer, H Tang, Y Ren, L Bohannon, D Jiang… - Clinical Nutrition, 2024 - Elsevier
Background & aims The COVID-19 pandemic continues to pose unprecedented challenges
to worldwide health. While vaccines are effective, additional strategies to mitigate the …

The effect of ginger and curcumin co-supplementation in postmenopausal women with osteoporosis: a randomised, triple-blind, placebo-controlled clinical trial

Y Salekzamani, SK Shakouri, N Dolatkhah… - Journal of Herbal …, 2023 - Elsevier
Introduction We aimed to examine the efficacy and safety of ginger and curcumin
supplementation in postmenopausal osteoporosis. Methods In this 4-month randomised …

The Use of Nigella sativa in Cardiometabolic Diseases

G Derosa, A D'Angelo, P Maffioli, L Cucinella… - Biomedicines, 2024 - mdpi.com
Nigella sativa L. is an herb that is commonly used in cooking and in traditional medicine,
particularly in Arab countries, the Indian subcontinent, and some areas of eastern Europe …

Utilization of Nanotechnology to Improve Bone Health in Osteoporosis Exploiting Nigella sativa and Its Active Constituent Thymoquinone

J Ahmad, HA Albarqi, MZ Ahmad, MAA Orabi, S Md… - Bioengineering, 2022 - mdpi.com
Osteoporosis, a chronic bone disorder, is one of the leading causes of fracture and morbidity
risk. Numerous medicinally important herbs have been evaluated for their efficacy in …

Advent of phytobiologics and nano-interventions for bone remodeling: a comprehensive review

A Gupta, SK Mehta, A Kumar… - Critical Reviews in …, 2023 - Taylor & Francis
Bone metabolism constitutes the intricate processes of matrix deposition, mineralization, and
resorption. Any imbalance in these processes leads to traumatic bone injuries and serious …