Biological characteristics and pathogenicity of Acanthamoeba

Y Wang, L Jiang, Y Zhao, X Ju, L Wang, L Jin… - Frontiers in …, 2023 - frontiersin.org
Acanthamoeba is an opportunistic protozoa, which exists widely in nature and is mainly
distributed in soil and water. Acanthamoeba usually exists in two forms, trophozoites and …

[HTML][HTML] Acanthamoeba keratitis–Clinical signs, differential diagnosis and treatment

N Szentmáry, L Daas, L Shi, KL Laurik, S Lepper… - Journal of current …, 2019 - Elsevier
Purpose To summarize actual literature data on clinical signs, differential diagnosis, and
treatment of acanthamoeba keratitis. Methods Review of literature. Results Clinical signs of …

Strategies for the prevention of contact lens‐related Acanthamoeba keratitis: a review

N Carnt, F Stapleton - Ophthalmic and physiological optics, 2016 - Wiley Online Library
Purpose Acanthamoeba keratitis is a severe, often sight threatening, corneal infection which
in Western countries is predominantly seen in daily wear of contact lenses. This review aims …

Advances in the management of Acanthamoeba keratitis: a review of the literature and synthesized algorithmic approach

AR Kaufman, EY Tu - The Ocular Surface, 2022 - Elsevier
Acanthamoeba keratitis (AK) is a severe cause of infectious keratitis and represents a
significant clinical challenge. Recent literature regarding AK epidemiology, diagnosis …

[HTML][HTML] The orphan drug for acanthamoeba keratitis (ODAK) trial: PHMB 0.08%(polihexanide) and placebo versus PHMB 0.02% and propamidine 0.1%

JKG Dart, V Papa, P Rama, KA Knutsson, S Ahmad… - Ophthalmology, 2024 - Elsevier
Purpose To compare topical PHMB (polihexanide) 0.02%(0.2 mg/ml)+ propamidine 0.1%(1
mg/ml) with PHMB 0.08%(0.8 mg/ml)+ placebo (PHMB 0.08%) for Acanthamoeba keratitis …

The impact of topical corticosteroid use before diagnosis on the outcome of Acanthamoeba keratitis

D Robaei, N Carnt, DC Minassian, JKG Dart - Ophthalmology, 2014 - Elsevier
Objective To examine the impact of topical corticosteroid use before the diagnosis of
Acanthamoeba keratitis (AK) on final visual outcomes and to determine the prognostic …

Combating Acanthamoeba spp. cysts: what are the options?

A Anwar, NA Khan, R Siddiqui - Parasites & vectors, 2018 - Springer
Acanthamoeba spp. are protist pathogens and causative agents of serious infections
including keratitis and granulomatous amoebic encephalitis. Its ability to convert into …

Contact lens associated microbial keratitis: practical considerations for the optometrist

AB Zimmerman, AD Nixon, EM Rueff - Clinical Optometry, 2016 - Taylor & Francis
Microbial keratitis (MK) is a corneal condition that encompasses several different pathogens
and etiologies. While contact lens associated MK is most often associated with bacterial …

The diagnosis and management of contact lens‐related microbial keratitis

N Carnt, C Samarawickrama, A White… - Clinical and …, 2017 - Taylor & Francis
Contact lens‐associated microbial keratitis poses a diagnostic dilemma for optometrists on
two fronts. The distinction between sterile inflammation and microbial infection is often …

Acanthamoeba Keratitis: an update on amebicidal and cysticidal drug screening methodologies and potential treatment with azole drugs

B Shing, M Balen, JH McKerrow… - Expert review of anti …, 2021 - Taylor & Francis
Introduction: Acanthamoeba encompasses several species of free-living ameba
encountered commonly throughout the environment. Unfortunately, these species of ameba …