Understanding the role of dopamine in cancer: past, present and future

CE Grant, AL Flis, BM Ryan - Carcinogenesis, 2022 - academic.oup.com
Abstract Dopamine (DA, 3-hydroxytyramine) is a member of the catecholamine family and is
classically characterized according to its role in the central nervous system as a …

Current and emerging medical therapies in pituitary tumors

N Sahakian, F Castinetti, T Brue, T Cuny - Journal of clinical medicine, 2022 - mdpi.com
Pituitary tumors (PT) represent in, the majority of cases, benign tumors for which surgical
treatment still remains, except for prolactin-secreting PT, the first-line therapeutic option …

Controlled release of dopamine coatings on titanium bidirectionally regulate osteoclastic and osteogenic response behaviors

M Wang, C Wang, Y Zhang, Y Lin - Materials Science and Engineering: C, 2021 - Elsevier
Bone diseases, for example, osteoporosis, cause excessive differentiation of osteoclasts
and decreased bone formation, resulting in imbalance of bone remodeling and poor …

A Somatostatin Receptor Subtype-3 (SST3) Peptide Agonist Shows Antitumor Effects in Experimental Models of Nonfunctioning Pituitary Tumors

MC Vázquez-Borrego, V Gupta, A Ibáñez-Costa… - Clinical Cancer …, 2020 - AACR
Purpose: Somatostatin analogues (SSA) are efficacious and safe treatments for a variety of
neuroendocrine tumors, especially pituitary neuroendocrine tumors (PitNET). Their …

Dopamine D1 receptor-mediated activation of the ERK signaling pathway is involved in the osteogenic differentiation of bone mesenchymal stem cells

CX Wang, XY Ge, MY Wang, T Ma, Y Zhang… - Stem Cell Research & …, 2020 - Springer
Background Osteogenic differentiation of bone mesenchymal stem cells (BMSCs) is
regulated by numerous signaling pathways. Dopamine (DA), a neurotransmitter, has …

Decoding signaling pathways involved in prolactin-induced neuroprotection: A review

G Molina-Salinas, NA Rivero-Segura… - Frontiers in …, 2021 - Elsevier
It has been well recognized that prolactin (PRL), a pleiotropic hormone, has many functions
in the brain, such as maternal behavior, neurogenesis, and neuronal plasticity, among …

The mechanism and pathways of dopamine and dopamine agonists in prolactinomas

X Liu, C Tang, G Wen, C Zhong, J Yang… - Frontiers in …, 2019 - frontiersin.org
Dopamine agonists such as bromocriptine and cabergoline are the predominant treatment
drugs for prolactinoma by inhibiting prolactin secretion and shrinking tumor size. However …

The dopaminergic control of Cushing's syndrome

R Pivonello, C Pivonello, C Simeoli… - Journal of …, 2022 - Springer
Abstract Cushing's Syndrome (CS), or chronic endogenous hypercortisolism, is a rare and
serious disease due to corticotroph pituitary (Cushing's disease, CD) and extra-pituitary …

Biguanides exert antitumoral actions in pituitary tumor cells through AMPK-dependent and-independent mechanisms

MC Vázquez-Borrego… - The Journal of …, 2019 - academic.oup.com
Abstract Context Pituitary neuroendocrine tumors (PitNETs) are a commonly underestimated
pathology in terms of incidence and associated morbimortality. Currently, an appreciable …

Resistance to dopamine agonists in pituitary tumors: molecular mechanisms

C Pivonello, R Patalano, M Negri, R Pirchio… - Frontiers in …, 2022 - frontiersin.org
Pituitary neuroendocrine tumors (PitNET) are commonly benign tumors accounting for 10-
25% of intracranial tumors. Prolactin-secreting adenomas represent the most predominant …