Using genetics for social science
KP Harden, PD Koellinger - Nature human behaviour, 2020 - nature.com
Social science genetics is concerned with understanding whether, how and why genetic
differences between human beings are linked to differences in behaviours and …
differences between human beings are linked to differences in behaviours and …
[HTML][HTML] Polygenic prediction of educational attainment within and between families from genome-wide association analyses in 3 million individuals
We conduct a genome-wide association study (GWAS) of educational attainment (EA) in a
sample of~ 3 million individuals and identify 3,952 approximately uncorrelated genome …
sample of~ 3 million individuals and identify 3,952 approximately uncorrelated genome …
Self-entropic broadening theory: Toward a new understanding of self and behavior change informed by psychedelics and psychosis
HM Dourron, C Strauss, PS Hendricks… - Pharmacological Reviews, 2022 - Elsevier
The extremes of human experiences, such as those occasioned by classic psychedelics and
psychosis, provide a rich contrast for understanding how components of these experiences …
psychosis, provide a rich contrast for understanding how components of these experiences …
Genome-wide analyses of ADHD identify 27 risk loci, refine the genetic architecture and implicate several cognitive domains
Attention-deficit hyperactivity disorder (ADHD) is a prevalent neurodevelopmental disorder
with a major genetic component. Here, we present a genome-wide association study meta …
with a major genetic component. Here, we present a genome-wide association study meta …
Genomic relationships, novel loci, and pleiotropic mechanisms across eight psychiatric disorders
Genetic influences on psychiatric disorders transcend diagnostic boundaries, suggesting
substantial pleiotropy of contributing loci. However, the nature and mechanisms of these …
substantial pleiotropy of contributing loci. However, the nature and mechanisms of these …
Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences
Humans vary substantially in their willingness to take risks. In a combined sample of over 1
million individuals, we conducted genome-wide association studies (GWAS) of general risk …
million individuals, we conducted genome-wide association studies (GWAS) of general risk …
Common brain disorders are associated with heritable patterns of apparent aging of the brain
Common risk factors for psychiatric and other brain disorders are likely to converge on
biological pathways influencing the development and maintenance of brain structure and …
biological pathways influencing the development and maintenance of brain structure and …
Investigating the genetic architecture of noncognitive skills using GWAS-by-subtraction
Little is known about the genetic architecture of traits affecting educational attainment other
than cognitive ability. We used genomic structural equation modeling and prior genome …
than cognitive ability. We used genomic structural equation modeling and prior genome …
Bivariate causal mixture model quantifies polygenic overlap between complex traits beyond genetic correlation
Accumulating evidence from genome wide association studies (GWAS) suggests an
abundance of shared genetic influences among complex human traits and disorders, such …
abundance of shared genetic influences among complex human traits and disorders, such …
Wrestling with social and behavioral genomics: risks, potential benefits, and ethical responsibility
In this consensus report by a diverse group of academics who conduct and/or are concerned
about social and behavioral genomics (SBG) research, the authors recount the often‐ugly …
about social and behavioral genomics (SBG) research, the authors recount the often‐ugly …