Epidemiologic, genetic, pathogenic, metabolic, epigenetic aspects involved in NASH-HCC: current therapeutic strategies

J Gutiérrez-Cuevas, S Lucano-Landeros… - Cancers, 2022 - mdpi.com
Simple Summary Hepatocellular carcinoma (HCC) is an aggressive human cancer and is
caused as consequences of chronic liver diseases. Although HCC is more common in …

[HTML][HTML] Hepatocellular carcinoma in non-alcoholic fatty liver disease: current progresses and challenges

YX Teng, S Xie, PP Guo, ZJ Deng… - Journal of Clinical …, 2022 - ncbi.nlm.nih.gov
The rising global prevalence of metabolic diseases has increased the prevalence of non-
alcoholic fatty liver disease (NAFLD), leading to an increase in cases of NAFLD-related …

[HTML][HTML] Atezolizumab plus bevacizumab versus lenvatinib for unresectable hepatocellular carcinoma: a large real-life worldwide population

A Casadei-Gardini, M Rimini, T Tada, G Suda… - European Journal of …, 2023 - Elsevier
Background and aims Atezolizumab plus bevacizumab and lenvatinib have not been
compared in a randomised controlled trial. We conducted a retrospective multi-centre study …

Durvalumab plus gemcitabine and cisplatin in advanced biliary tract cancer: An early exploratory analysis of real‐world data

M Rimini, L Fornaro, S Lonardi, M Niger… - Liver …, 2023 - Wiley Online Library
Abstract Background The TOPAZ‐1 phase III trial reported a survival benefit with the anti‐
programmed death cell ligand 1 (anti‐PD‐L1) durvalumab in combination with gemcitabine …

[HTML][HTML] Atezolizumab plus bevacizumab versus lenvatinib or sorafenib in non-viral unresectable hepatocellular carcinoma: an international propensity score matching …

M Rimini, L Rimassa, K Ueshima, V Burgio, S Shigeo… - ESMO open, 2022 - Elsevier
Background A growing body of evidence suggests that non-viral hepatocellular carcinoma
(HCC) might benefit less from immunotherapy. Materials and methods We carried out a …

Survival outcomes from atezolizumab plus bevacizumab versus Lenvatinib in Child Pugh B unresectable hepatocellular carcinoma patients

M Rimini, M Persano, T Tada, G Suda… - Journal of Cancer …, 2023 - Springer
Introduction The best first-line treatment for patients with advanced hepatocellular carcinoma
(HCC) and Child–Pugh (CP) class B remains unknown. The aim of the present study was to …

Phenotypes of Metabolic Dysfunction–Associated Steatotic Liver Disease–Associated Hepatocellular Carcinoma

J Rivera-Esteban, S Muñoz-Martínez, M Higuera… - Clinical …, 2024 - Elsevier
Hepatocellular carcinoma (HCC) typically develops as a consequence of liver cirrhosis, but
HCC epidemiology has evolved drastically in recent years. Metabolic dysfunction …

Stereotactic body radiotherapy for hepatocellular carcinoma: meta-analysis and International Stereotactic Radiosurgery Society practice guidelines

SH Bae, SJ Chun, JH Chung, E Kim, JK Kang… - International Journal of …, 2023 - Elsevier
Purpose This systematic review and meta-analysis reports on outcomes and hepatic toxicity
rates following stereotactic body radiotherapy (SBRT) for liver confined hepatocellular …

[HTML][HTML] Non-alcoholic fatty liver disease-related hepatocellular carcinoma

D Daher, KS El Dahan, AG Singal - Journal of Liver Cancer, 2023 - synapse.koreamed.org
Non-alcoholic fatty liver disease (NAFLD), one of the most common causes of liver disease,
is an increasingly common cause of hepatocellular carcinoma (HCC). Several demographic …

Role of etiology in hepatocellular carcinoma patients treated with lenvatinib: a counterfactual event-based mediation analysis

R Sacco, D Ramai, R Tortora, GG di Costanzo… - Cancers, 2023 - mdpi.com
Simple Summary Hepatocellular carcinoma is the fifth most common cancer worldwide. For
patients with advanced hepatocellular carcinoma, therapeutic options are limited. Lenvatinib …