[HTML][HTML] The role of Wnt signaling pathway in tumor metabolic reprogramming
Y Mo, Y Wang, L Zhang, L Yang, M Zhou, X Li… - Journal of …, 2019 - ncbi.nlm.nih.gov
The occurrence and development of tumors is a complex process involving long-term multi-
factor participation. In this process, tumor cells from a set of abnormal metabolic patterns that …
factor participation. In this process, tumor cells from a set of abnormal metabolic patterns that …
Multifaceted role of PRDM proteins in human cancer
The PR/SET domain family (PRDM) comprise a family of genes whose protein products
share a conserved N-terminal PR [PRDI-BF1 (positive regulatory domain I-binding factor 1) …
share a conserved N-terminal PR [PRDI-BF1 (positive regulatory domain I-binding factor 1) …
The RNA methyltransferase METTL16 enhances cholangiocarcinoma growth through PRDM15-mediated FGFR4 expression
Abstract Background RNA N6-Methyladenosine (m6A) modification is implicated in the
progression of human cancers including cholangiocarcinoma (CCA). METTL16 is recently …
progression of human cancers including cholangiocarcinoma (CCA). METTL16 is recently …
Lineage specification and pluripotency revealed by transcriptome analysis from oocyte to blastocyst in pig
Q Kong, X Yang, H Zhang, S Liu, J Zhao… - The FASEB …, 2020 - Wiley Online Library
The inner cell mass (ICM) in blastocyst is the origin of all somatic and germ cells in
mammals and pluripotent stem cells (PSCs) in vitro. As the conserved principles between …
mammals and pluripotent stem cells (PSCs) in vitro. As the conserved principles between …
Nuclear receptor-SINE B1 network modulates expanded pluripotency in blastoids and blastocysts
Embryonic stem cells possess the remarkable ability to self-organize into blastocyst-like
structures upon induction. These stem cell-based embryo models serve as invaluable …
structures upon induction. These stem cell-based embryo models serve as invaluable …
Evolutionary origin of vertebrate OCT4/POU5 functions in supporting pluripotency
W Sukparangsi, E Morganti, M Lowndes… - Nature …, 2022 - nature.com
The support of pluripotent cells over time is an essential feature of development. In eutherian
embryos, pluripotency is maintained from naïve states in peri-implantation to primed …
embryos, pluripotency is maintained from naïve states in peri-implantation to primed …
Targeting wnt signaling for gastrointestinal cancer therapy: Present and evolving views
Simple Summary Therapeutic targeting of Wnt has long been suggested for gastrointestinal
(GI) cancer treatment because deregulation of Wnt signaling is associated with GI cancers …
(GI) cancer treatment because deregulation of Wnt signaling is associated with GI cancers …
PRDM15 is a key regulator of metabolism critical to sustain B-cell lymphomagenesis
Abstract PRDM (PRDI-BF1 and RIZ homology domain containing) family members are
sequence-specific transcriptional regulators involved in cell identity and fate determination …
sequence-specific transcriptional regulators involved in cell identity and fate determination …
The duality of PRDM proteins: epigenetic and structural perspectives
F Di Tullio, M Schwarz, H Zorgati, S Mzoughi… - The FEBS …, 2022 - Wiley Online Library
PRDF1 and RIZ1 homology domain containing (PRDMs) are a subfamily of Krüppel‐like
zinc finger proteins controlling key processes in metazoan development and in cancer …
zinc finger proteins controlling key processes in metazoan development and in cancer …
Ribosomal proteins regulate 2-cell-stage transcriptome in mouse embryonic stem cells
A rare sub-population of mouse embryonic stem cells (mESCs), the 2-cell-like cell, is defined
by the expression of MERVL and 2-cell-stage-specific transcript (2C transcript). Here, we …
by the expression of MERVL and 2-cell-stage-specific transcript (2C transcript). Here, we …