Enzyme nomenclature and classification: The state of the art

AG McDonald, KF Tipton - The FEBS journal, 2023 - Wiley Online Library
The IUBMB enzyme classification system, available at the IUBMB ExplorEnz website, uses a
four‐component number (the EC number) that identifies an enzyme in terms of reaction …

Transformation of biomass into commodity chemicals using enzymes or cells

AJJ Straathof - Chemical reviews, 2014 - ACS Publications
Biomass can be classified broadly as all the matter on the earth's surface of recent biological
origin. 1 Biomass includes plant materials such as trees, grasses, agricultural crops, algal …

[HTML][HTML] Fundamental behaviors emerge from simulations of a living minimal cell

ZR Thornburg, DM Bianchi, TA Brier, BR Gilbert… - Cell, 2022 - cell.com
We present a whole-cell fully dynamical kinetic model (WCM) of JCVI-syn3A, a minimal cell
with a reduced genome of 493 genes that has retained few regulatory proteins or small …

eQuilibrator 3.0: a database solution for thermodynamic constant estimation

ME Beber, MG Gollub, D Mozaffari… - Nucleic acids …, 2022 - academic.oup.com
Abstract eQuilibrator (equilibrator. weizmann. ac. il) is a database of biochemical equilibrium
constants and Gibbs free energies, originally designed as a web-based interface. While the …

Glycolytic strategy as a tradeoff between energy yield and protein cost

A Flamholz, E Noor, A Bar-Even… - Proceedings of the …, 2013 - National Acad Sciences
Contrary to the textbook portrayal of glycolysis as a single pathway conserved across all
domains of life, not all sugar-consuming organisms use the canonical Embden–Meyerhoff …

eQuilibrator—the biochemical thermodynamics calculator

A Flamholz, E Noor, A Bar-Even… - Nucleic acids research, 2012 - academic.oup.com
The laws of thermodynamics constrain the action of biochemical systems. However,
thermodynamic data on biochemical compounds can be difficult to find and is cumbersome …

Rigorous data‐driven computation of spectral properties of Koopman operators for dynamical systems

MJ Colbrook, A Townsend - Communications on Pure and …, 2024 - Wiley Online Library
Koopman operators are infinite‐dimensional operators that globally linearize nonlinear
dynamical systems, making their spectral information valuable for understanding dynamics …

Global characterization of in vivo enzyme catalytic rates and their correspondence to in vitro kcat measurements

D Davidi, E Noor, W Liebermeister… - Proceedings of the …, 2016 - National Acad Sciences
Turnover numbers, also known as k cat values, are fundamental properties of enzymes.
However, k cat data are scarce and measured in vitro, thus may not faithfully represent the in …

Pathway thermodynamics highlights kinetic obstacles in central metabolism

E Noor, A Bar-Even, A Flamholz, E Reznik… - PLoS computational …, 2014 - journals.plos.org
In metabolism research, thermodynamics is usually used to determine the directionality of a
reaction or the feasibility of a pathway. However, the relationship between thermodynamic …

Glucose oxidase: natural occurrence, function, properties and industrial applications

CM Wong, KH Wong, XD Chen - Applied microbiology and biotechnology, 2008 - Springer
Glucose oxidase (GOX) from Aspergillus niger is a well-characterised glycoprotein
consisting of two identical 80-kDa subunits with two FAD co-enzymes bound. Both the DNA …