Proteins can be the root cause of a disease, and they can be used to cure it. The need to
identify these critical actors was recognized early (1951) by Sanger; the first biopolymer …

Nanopores are promising sensing devices that can be used for the detection of analytes at
the single molecule level. It is of importance to understand and model the current response …

Established methods for characterizing proteins typically require physical or chemical
modification steps or cannot be used to examine individual molecules in solution. Ionic …

The primary structure of a protein consists of a sequence of amino acids and is a key factor
in determining how a protein folds and functions. However, conventional methods for …

This paper demonstrates that high-bandwidth current recordings in combination with low-
noise silicon nitride nanopores make it possible to determine the molecular volume …

The prospect of characterizing individual nanoparticles, molecules, or DNA base pairs has
generated considerable interest in resistive pulse sensing. In addition to size and …

Since the first reported use of a biological ion channel to detect differences in single
stranded genomic base pairs in 1996, a renaissance in nanoscale resistive pulse sensors …

In two decades, the solid state and polymer nanopores became attractive method for the
protein sensing with high specificity and sensitivity. They also allow the characterization of …

The contact of nanoparticles with biological fluids such as serum results in rapid adsorption
of proteins at the nanoparticle surface in a layer known as the “protein corona”. Protein …

Solid-state nanopores with a through-hole diameter of less than a few hundred nanometers
can detect single nanoparticles owing to the ionic current flowing through the nanopore …