Despite decades of laboratory, epidemiological and clinical research, breast cancer
incidence continues to rise. Breast cancer remains the leading cancer-related cause of …

The huge communities of residential microbes, including bacteria, viruses, Archaea, and
Eukaryotes, that colonize humans are increasingly recognized as playing important roles in …

The NCCN Guidelines for Genetic/Familial High-Risk Assessment: Breast, Ovarian, and
Pancreatic focus primarily on assessment of pathogenic or likely pathogenic variants …

Importance The influence of menopausal hormone therapy on breast cancer remains
unsettled with discordant findings from observational studies and randomized clinical trials …

Hereditary breast and ovarian cancer syndrome (HBOC) is clinically defined by family
history criteria, and molecularly defined by identification of germline pathogenic variants …

Importance Health outcomes from the Women's Health Initiative Estrogen Plus Progestin
and Estrogen-Alone Trials have been reported, but previous publications have generally not …

Pelvic endometriosis is a complex syndrome characterized by an estrogen-dependent
chronic inflammatory process that affects primarily pelvic tissues, including the ovaries. It is …

The history of hormone replacement therapy (HRT) started in the 1960s, with very high
popularity in the 1990s. The first clinical trials on HRT and chronic postmenopausal …

Background In this review, we examine the continually expanding and increasingly
compelling data linking radiation and various chemicals in our environment to the current …

This Review is intended to help clinicians, patients, and the public make informed decisions
about statin therapy for the prevention of heart attacks and strokes. It explains how the …