The cutaneous drug delivery represents an attractive option for the management of skin
diseases. However, the skin has a very complex morphological structure, although the skin …

The skin has been employed as a delivery route for localized as well as systemic delivery of
drugs. However, the Stratum corneum (SC) of the skin act as a main barrier for the …

Nanotherapeutics in cancer treatment are dominating global science and research, and
have been recognized as the pioneering medical care regimen. Raloxifene (RLN) has been …

Rheumatoid arthritis (RA), an autoimmune inflammatory disorder is currently incurable.
Methotrexate and Teriflunomide are routinely prescribed drugs but their uses are limited due …

Atopic dermatitis is a prevalent chronic skin inflammation affecting 2.1 to 4.1% of adults
globally. The complexity of its pathogenesis and the relapsing nature make it challenging to …

In this study, liposome and transfersome were successfully constructed using molecular
dynamics simulation. Three drugs with different polarity, including 5-fluorouracil …

Recently, bioinspired cell-derived nanovesicles (CDNs) have gained much interest in the
field of nanomedicine due to the preservation of biomolecular structure characteristics …

The development of externally controlled drug delivery systems that can rapidly trigger drug
release is widely expected to change the landscape of future drug carriers. In this study, a …

Transdermal drug delivery helps to circumvent the first-pass effect of drugs and to avoid drug-
induced gastrointestinal tract irritation, compared with oral administration. With the extensive …

The transdermal drug delivery system (TDDS) is a promising and innovative approach to
drug delivery because of its noninvasiveness, potential for localized and prolonged drug …