Meiotic drivers are genetic variants that selfishly manipulate the production of gametes to
increase their own rate of transmission, often to the detriment of the rest of the genome and …

Selfishness is pervasive and manifests at all scales of biology, from societies, to individuals,
to genetic elements within a genome. The relentless struggle to seek evolutionary …

Existing human genome assemblies have almost entirely excluded repetitive sequences
within and near centromeres, limiting our understanding of their organization, evolution, and …

Sex differences in overall recombination rates are well known, but little theoretical or
empirical attention has been given to how and why sexes differ in their recombination …

Meiosis is a key event of sexual life cycles in eukaryotes. Its mechanistic details have been
uncovered in several model organisms, and most of its essential features have received …

To understand evolutionary factors that maintain complex trait variation, we sequenced
genomes from a single population of the plant Mimulus guttatus, identifying hundreds of …

Simple non-coding tandem repeats known as satellite DNA are observed widely across
eukaryotes. These repeats occupy vast regions at the centromere and pericentromere of …

Scientists are rapidly developing synthetic gene drive elements intended for release into
natural populations. These are intended to control or eradicate disease vectors and pests, or …

Genomic conflicts may play a central role in the evolution of reproductive barriers. Theory
predicts that early-onset hybrid inviability may stem from conflict between parents for …

Highlights•Cortical CDC42 signaling leads to asymmetric tyrosination of meiosis I spindle
microtubules.•Centromeric DNA expansion recruits more CenH3, increases centromere …