Home as the new frontier for the treatment of COVID-19: the case for anti-inflammatory agents

N Perico, M Cortinovis, F Suter… - The Lancet Infectious …, 2023 - thelancet.com
Summary COVID-19, caused by SARS-CoV-2, is characterised by a broad spectrum of
symptom severity that requires varying amounts of care according to the different stages of …

Metabolic alterations upon SARS-CoV-2 infection and potential therapeutic targets against coronavirus infection

P Chen, M Wu, Y He, B Jiang, ML He - Signal Transduction and …, 2023 - nature.com
Abstract The coronavirus disease 2019 (COVID-19) caused by coronavirus SARS-CoV-2
infection has become a global pandemic due to the high viral transmissibility and …

Long COVID or post-COVID-19 condition: past, present and future research directions

C Fernández-de-Las-Peñas, AV Raveendran… - Microorganisms, 2023 - mdpi.com
The presence of symptoms after an acute SARS-CoV-2 infection (long-COVID) has become
a worldwide healthcare emergency but remains underestimated and undertreated due to a …

Ibuprofen, other NSAIDs and COVID-19: a narrative review

W Laughey, I Lodhi, G Pennick, L Smart, O Sanni… - …, 2023 - Springer
At the start of the coronavirus disease 2019 (COVID-19) pandemic (March 2020), there was
speculation that non-steroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen, used to …

Precision management of post‐COVID pain: An evidence and clinical‐based approach

C Fernández‐de‐las‐Peñas, J Nijs… - … Journal of Pain, 2023 - Wiley Online Library
Background Pain after a SARS‐CoV‐2 acute infection (post‐COVID pain) is becoming a
new healthcare emergency but remains underestimated and most likely undertreated due to …

Angiotensin-converting enzyme 2 expression and severity of SARS-CoV-2 infection

S Alabsi, A Dhole, S Hozayen, SA Chapman - Microorganisms, 2023 - mdpi.com
Angiotensin-converting enzyme 2 (ACE2), first discovered in 2000, serves as an important
counterregulatory enzyme to the angiotensin II-mediated vasoconstrictive, pro-inflammatory …

[HTML][HTML] Effects of Common Anti-Inflammatories on Adenovirus Entry and Their Physicochemical Properties: An In-Depth Study Using Cellular and Animal Models

HR Galvan-Salazar, M Delgado-Machuca… - Microbiology …, 2024 - mdpi.com
The severity of adenovirus infection or the success of adenovirus-vectorized gene therapy
largely depends on the efficiency of viral entry into cells. Various drugs can alter viral entry …

Short-term celecoxib (celebrex) adjuvant therapy: a clinical trial study on COVID-19 patients

H Ghaznavi, Z Mohammadghasemipour… - …, 2022 - Springer
Background It is known that severe acute respiratory coronavirus 2 (SARS-CoV-2) is the
viral strain responsible for the recent coronavirus disease 2019 (COVID-19) pandemic …

Altered plasma levels of the SARS-CoV-2-related proteins ACE2 and TMPRSS2 in patients with Crohn's disease

J Sáez-Leyva, MP Lennol, C Avilés-Granados… - Scientific Reports, 2024 - nature.com
The SARS-CoV-2 coronavirus infects cells through the cellular receptor angiotensin-
converting enzyme 2 (ACE2), and the protease TMPRSS2 for the priming of viral spike …

Integrated analgesic care in the current human monkeypox outbreak: perspectives on an integrated and holistic approach combining old allies with innovative …

GH Hans, D Wildemeersch, I Meeus - Medicina, 2022 - mdpi.com
Monkeypox (MPX) is a zoonotic infection caused by an orthopoxvirus that is endemic to
Central and Western Africa. The MPX virus is a part of the same family of viruses as the …