Endothelial dysfunction in COVID-19: an overview of evidence, biomarkers, mechanisms and potential therapies

S Xu, I Ilyas, J Weng - Acta Pharmacologica Sinica, 2023 - nature.com
The fight against coronavirus disease 2019 (COVID-19) caused by SARS-CoV-2 infection is
still raging. However, the pathophysiology of acute and post-acute manifestations of COVID …

Cytokine storm in COVID-19: immunopathogenesis and therapy

C Zanza, T Romenskaya, AC Manetti, F Franceschi… - Medicina, 2022 - mdpi.com
A cytokine storm is a hyperinflammatory state secondary to the excessive production of
cytokines by a deregulated immune system. It manifests clinically as an influenza-like …

Innate and adaptive immunity during SARS-CoV-2 infection: biomolecular cellular markers and mechanisms

B Brown, V Ojha, I Fricke, SA Al-Sheboul, C Imarogbe… - Vaccines, 2023 - mdpi.com
The coronavirus 2019 (COVID-19) pandemic was caused by a positive sense single-
stranded RNA (ssRNA) severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) …

Myocardial pathology in COVID-19-associated cardiac injury: a systematic review

A Maiese, P Frati, F Del Duca, P Santoro, AC Manetti… - Diagnostics, 2021 - mdpi.com
Coronavirus disease 2019 (COVID-19) can potentially affect all organs owing to the
ubiquitous diffusion of the angiotensin-converting enzyme II (ACE2) receptor-binding …

Reactive oxygen species in the adverse outcome pathway framework: Toward creation of harmonized consensus key events

S Tanabe, J O'Brien, KE Tollefsen, Y Kim… - Frontiers in …, 2022 - frontiersin.org
Reactive oxygen species (ROS) and reactive nitrogen species (RNS) are formed as a result
of natural cellular processes, intracellular signaling, or as adverse responses associated …

Antiviral therapy for COVID-19: Derivation of optimal strategy based on past antiviral and favipiravir experiences

K Shiraki, N Sato, K Sakai, S Matsumoto… - Pharmacology & …, 2022 - Elsevier
Favipiravir, a broad-spectrum RNA-dependent RNA polymerase inhibitor, inhibits the
replication of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) at …

Unraveling muscle impairment associated with COVID-19 and the role of 3D culture in its investigation

MLGA Seixas, LP Mitre, S Shams, GB Lanzuolo… - Frontiers in …, 2022 - frontiersin.org
COVID-19, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has
been considered a public health emergency, extensively investigated by researchers …

Association of circulating biomarkers with illness severity measures differentiates myalgic encephalomyelitis/chronic fatigue syndrome and post-COVID-19 condition: a …

JC Domingo, F Battistini, B Cordobilla… - Journal of Translational …, 2024 - Springer
Background Accumulating evidence suggests that autonomic dysfunction and persistent
systemic inflammation are common clinical features in myalgic encephalomyelitis/chronic …

[HTML][HTML] Liver pathology in COVID-19 related death and leading role of autopsy in the pandemic

M Zanon, M Neri, S Pizzolitto, D Radaelli… - World Journal of …, 2023 - ncbi.nlm.nih.gov
Liver pathology in COVID-19 related death and leading role of autopsy in the pandemic - PMC
Back to Top Skip to main content NIH NLM Logo Access keys NCBI Homepage MyNCBI …

SARS-CoV-2 infection dysregulates the expression of clinically relevant drug metabolizing enzymes in Vero E6 cells and membrane transporters in human lung …

CK Nwabufo, MT Hoque, L Yip, M Khara… - Frontiers in …, 2023 - frontiersin.org
SARS-CoV-2-mediated interactions with drug metabolizing enzymes and membrane
transporters (DMETs) in different tissues, especially lung, the main affected organ may limit …