Multicomponent reactions and photo/electrochemistry join forces: atom economy meets energy efficiency

GA Coppola, S Pillitteri, EV Van der Eycken… - Chemical Society …, 2022 - pubs.rsc.org
Visible-light photoredox catalysis has been regarded as an extremely powerful tool in
organic chemistry, bringing the spotlight back to radical processes. The versatility of …

Recent Advances in Multicomponent Electro‐Organic (Electrochemical) Synthesis of Heterocycles

S Imeni, A Makarem… - Asian Journal of Organic …, 2023 - Wiley Online Library
In terms of pharmaceuticals and biological applications, synthesis of complex organic
molecules is a significant and fast‐developing area. In this context, organic electrosynthesis …

Metal- and Oxidant-Free Green Three-Component Desulfurization and Deamination Condensation Approach to Fully Substituted 1H-1,2,4-Triazol-3-amines and …

W Guo, G Liu, L Deng, W Mei, X Zou… - The Journal of …, 2021 - ACS Publications
A metal-and oxidant-free three-component desulfurization and deamination condensation of
amidines, isothiocyanates, and hydrazines for the synthesis of structurally diverse fully …

Electro-organic synthesis: an environmentally benign alternative for heterocycle synthesis

S Devi, D Wadhwa, J Sindhu - Organic & biomolecular chemistry, 2022 - pubs.rsc.org
Heterocyclic compounds are considered to be one of the most established structural classes
due to their extensive application in agrochemicals, pharmaceuticals and organic materials …

Electro-Oxidative sp3 C–H Bond Functionalization and Annulation Cascade: Synthesis of Novel Heterocyclic Substituted Indolizines

BK Malviya, AK Jassal, M Karnatak… - The Journal of …, 2022 - ACS Publications
Indolizine derivatives are prevalent in many synthetic intermediates, pharmaceuticals, and
organic materials. Herein, we report a novel electro-oxidative cascade cyclization reaction …

Green Synthesis of Aromatic Nitrogen-Containing Heterocycles by Catalytic and Non-Traditional Activation Methods

RB Vlocskó, G Xie, B Török - Molecules, 2023 - mdpi.com
Recent advances in the environmentally benign synthesis of aromatic N-heterocycles are
reviewed, focusing primarily on the application of catalytic methods and non-traditional …

Direct Synthesis of Alkylthioimidazoles: One‐Pot Three‐Component Cross‐Coupling Mediated by Paired Electrolysis

J Yang, T Zeng, K Yan, Z Qin… - Advanced Synthesis & …, 2022 - Wiley Online Library
The direct synthesis of alkylthioimidazoles was initially accomplished via a one‐pot three‐
component cross‐coupling mediated by a paired electrolysis strategy using non‐activated …

A Review on Chemistry and Methods of Synthesis of 1, 2, 4‐Triazole Derivatives

S Couto Rodrigues… - The Chemical …, 2025 - Wiley Online Library
This review provides a comprehensive overview of research on 1, 2, 4‐triazoles conducted
over the last fifteen years. 1, 2, 4‐Triazoles are highly significant in the pharmaceutical …

Electrochemical Generation of Nitrogen‐centered Radicals and its Application for the Green Synthesis of Heterocycles

K Titenkova, DA Chaplygin, LL Fershtat - ChemElectroChem, 2024 - Wiley Online Library
Electrochemistry became a unique and powerful tool for the preparation of a plethora of
valuable chemical species including functional materials, drug candidates and clinically …

Synthesis of multi-substituted 1, 2, 4-triazoles utilising the ambiphilic reactivity of hydrazones

H Matsuzaki, N Takeda, M Yasui, M Okazaki… - Chemical …, 2021 - pubs.rsc.org
The synthesis of N-alkyl-1H-1, 2, 4-triazoles from N, N-dialkylhydrazones and nitriles via
formal [3+ 2] cycloaddition including the C-chlorination/nucleophilic addition/cyclisation …