Alzheimer's disease (AD) represents the most frequent type of dementia in elderly people.
Two major forms of the disease exist: sporadic-the causes of which have not yet been fully …

Cholesterol homeostasis is essential in normal physiology of all cells. One of several
proteins involved in cholesterol homeostasis is the ATP-binding cassette transporter A1 …

Vector-borne illnesses comprise a significant portion of human maladies, representing 17%
of global infections. Transmission of vector-borne pathogens to mammals primarily occurs …

Although Flaviviruses such as dengue (DENV) and zika (ZIKV) virus are important human
pathogens, an effective vaccine or antiviral treatment against them is not available. Hence …

Oropouche orthobunyavirus (OROV; Peribunyaviridae) is a mosquito-transmitted virus that
causes widespread human febrile illness in South America, with occasional progression to …

Highlights•Host blood components affect mosquito susceptibility to arboviruses in diverse
manners.•The integrity of gut barriers affects the acquisition of viruses from the host's …

There are complex temporal and spatial interactions between insects and microbes.
Previously, the function of microbial virulence factors has been identified and characterized …

Dengue virus (DENV) transmission from humans to mosquitoes is a poorly documented, but
critical component of DENV epidemiology. Magnitude of viremia is the primary determinant …

With the emergence of new variant strains resulting from high mutation rates and genome
recombination, avian infectious bronchitis virus (IBV) has caused significant economic …

Cellular cholesterol plays an important role in the life cycles of enveloped viruses. Previous
studies by our group and other groups have demonstrated that the depletion of cellular …