Heterocycles form by far the largest of the classical divisions of organic chemistry. Moreover,
they are of immense importance not only both biologically and industrially but to the …

In the recent past, the design and synthesis of peptide mimics (peptidomimetics) has
received much attention. This because they have shown in many cases enhanced …

The synthesis, the chemical and photochemical reactivity, and the use of 1, 2, 4-oxadiazoles
in materials and as bioactive compounds have been reviewed. The material in this survey …

This review covers up to 2010 and some available references of 2011 of synthetic advances
in the Biginelli reaction, including recent mechanistic advances, new building blocks, new …

Heterocycles form by far the largest of the classical divisions of organic chemistry. Moreover,
they are of immense importance not only both biologically and industrially but to the …

Abstract A series of new 1, 6-dihydropyrimidin-2-thiol derivatives (scaffold A) as VEGFR-2
inhibitors has been designed and synthesized. Compounds 3a, 3b, 3e and 4b have been …

The synthesis, selectivity, rat pharmacokinetic profile, and drug metabolism profiles of a
series of potent fluoroolefin-derived DPP-4 inhibitors (4) are reported. A radiolabeled …

An efficient TaBr5 (5–10mol%)-catalyzed Biginelli reaction under solvent-free conditions for
one-pot syntheses of 3, 4-dihydropyrimidin-2-(1H)-ones (DHPMs) and their thione analogs …

1.1. Fragments. The central idea in fragment-based discovery is that screening a target
against a small number (as few as 500 compounds) of low molecular weight compounds …

Due to their unique properties, ionic liquids (ILs) have become increasingly popular over the
last few years in the field of green organic synthesis. This review provides an introduction to …