RNA modification is manifested as chemically altered nucleotides, widely exists in diverse
natural RNAs, and is closely related to RNA structure and function. Currently, mRNA-based …

Cancer is a disease that poses a serious threat to human health, the occurrence and
development of which involves complex molecular mechanisms. Long non-coding RNAs …

The potential of synthetic mRNA as a genetic carrier has increased its application in
scientific fields. Because the 5′ cap regulates the stability and translational activity of …

RNA degradation is a key process in the regulation of gene expression. In all organisms,
RNA degradation participates in controlling coding and non-coding RNA levels in response …

Small interfering RNAs (siRNAs), comprising 21–23 nucleotides, function by complementary
binding to specific mRNA sequences, thereby suppressing target protein expression …

In processes regulated by quorum sensing (QS) bacteria respond to the concentration of
autoinducers in the environment to engage in group behaviours. Autoinducer-2 (AI-2) is …

Labeled RNAs are invaluable probes for investigation of RNA function and localization.
However, mRNA labeling remains challenging. Here, we developed an improved method for …

Following the success of mRNA vaccines against COVID-19, mRNA-based therapeutics
have now become a great interest and potential. The development of this approach has …

RNA labeling is an invaluable tool for investigation of the function and localization of nucleic
acids. Labels are commonly incorporated into 3′ end of RNA and the primary enzyme used …

Protein-nucleic acid interactions play important roles in biological processes such as
transcription, recombination, and RNA metabolism. Experimental methods to study protein …