Although the phosphorus atom is found in a variety of oxidation states, most of the
phosphorus‐containing molecules of pharmacological importance possess phosphorus in …

Bones provide essential functions and are sites of unique biochemistry and specialized
cells, but can also be sites of disease. The treatment of bone disorders and neoplasia has …

Abstract The bisphosphonates ((HO) 2 P (O) CR 1 R 2 P (O)(OH) 2, BPs) were first shown to
inhibit bone resorption in the 1960s, but it was not until 30 years later that a detailed …

Abstract Hypochlorous acid (HOCl)/hypochlorite (ClO−) was a biologically important
component of reactive oxygen species (ROS) and plays a key role in human immune …

Bisphosphonate‐related osteonecrosis of the jaw (BRONJ) is a detrimental side effect of the
long‐term administration of bisphosphonates. Although macrophages were reported to be …

Metal-organophosphonates can be a superior alternative to the widely-explored carboxylate
based metal organic frameworks (MOFs) as they exhibit better heat resistance and air …

The development of stimuli-responsive nanomedicines with tunable cargo release is
gathering an increased applicability in bone regeneration and precision biomedicine. Yet …

Osteoclasts are large multinucleated cells exquisitely adapted to resorb bone matrix. Like
other eukaryotes, osteoclasts possess an elaborate ensemble of intracellular organelles …

Brain calcifications are commonly detected in aged individuals and accompany numerous
brain diseases, but their functional importance is not understood. In cases of primary familial …

DOI: 10.1002/adma. 201700131 from the primary tumor and colonize in distant sites.
Tracking the spread of cancer is a major challenge, particularly when it disseminates to …