B cell metabolism in autoimmune diseases: signaling pathways and interventions
Autoimmune diseases are heterogeneous disorders believed to stem from the immune
system's inability to distinguish between auto-and foreign-antigens. B lymphocytes serve a …
system's inability to distinguish between auto-and foreign-antigens. B lymphocytes serve a …
Renal tissue expression of baff and baff receptors is associated with proliferative lupus nephritis
M Marín-Rosales, CA Palafox-Sánchez… - Journal of Clinical …, 2022 - mdpi.com
Background: The B-cell activating factor (BAFF) controls the maturation and survival of B
cells. An imbalance in this cytokine has been associated with systemic autoimmunity in SLE …
cells. An imbalance in this cytokine has been associated with systemic autoimmunity in SLE …
Associations between TNFSF13B polymorphisms and primary Sjögren's syndrome susceptibility in primary Sjögren's syndrome patients: A meta‐analysis
A Zheng, N Hu, J Xu, Y Yuan, S Zhang… - Immunity …, 2023 - Wiley Online Library
Objective B‐cell activating factor (BAFF) is a key regulator of primary Sjögren's syndrome
(pSS), which is characterized by B‐lymphocyte hyperactivity. BAFF, also known as tumor …
(pSS), which is characterized by B‐lymphocyte hyperactivity. BAFF, also known as tumor …
TNFSF13B rs9514828 C>T Polymorphism is Associated with Incidence of Atherosclerosis and Therapeutic Outcomes in Patients with Systemic Lupus Erythematosus
Background Systemic lupus erythematosus (SLE) is a complex autoimmune disease with
numerous clinical manifestations. Organ involvement can aggravate patients with SLE and …
numerous clinical manifestations. Organ involvement can aggravate patients with SLE and …
Pre-and post-treatment serum BAFF levels and BAFF gene polymorphisms in patients with Graves' disease
T Dhaouadi, I Rojbi, S Ghammouki… - Endocrine …, 2023 - Taylor & Francis
Background B cell activating factor (BAFF), a crucial factor for B cell survival and
differentiation, has been linked to several autoimmune conditions. The aim of this study was …
differentiation, has been linked to several autoimmune conditions. The aim of this study was …
Association between BAFF gene polymorphism and systemic lupus erythematosus: a meta-analysis
Q Wu, Q Zhang, DQ Ye - Egyptian Journal of Medical Human Genetics, 2024 - Springer
Objective To inquire into the association from BAFF gene promoter-871C> T single
nucleotide polymorphisms (SNP) to the etiopathogenesis of systemic lupus erythematosus …
nucleotide polymorphisms (SNP) to the etiopathogenesis of systemic lupus erythematosus …
B-lymphocyte-activating factor is a potential biomarker associated with susceptibility to Graves' disease in Iraqi women
HY Ibrahim, GM Sulaiman, AH Ad'hiah… - Egyptian Journal of …, 2023 - Springer
Background B-lymphocyte-activating factor (BAFF) is a cytokine involved in regulating the
development and maturation of B lymphocyte and has been shown to be up-regulated in …
development and maturation of B lymphocyte and has been shown to be up-regulated in …
Deciphering Cell-types and Gene Signatures Associated with Disease Activity in Rheumatoid Arthritis using Single Cell RNA-sequencing
M Binvignat, BY Miao, C Wibrand, MM Yang… - bioRxiv, 2023 - biorxiv.org
Objective Single cell profiling of synovial tissue has previously identified gene signatures
associated with rheumatoid arthritis (RA) pathophysiology, but synovial tissue is difficult to …
associated with rheumatoid arthritis (RA) pathophysiology, but synovial tissue is difficult to …